Predictability of Intraocular Lens Calculation and Early Refractive Status

VanderVeen, Deborah K.; Nizam, Azhar; Lynn, Michael; Bothun, Erick D.; McClatchey, Scott K.; Weakley, David R.; DuBois, Lindreth; Lambert, Scott R.

doi:10.1001/archophthalmol.2011.358

Cited by 46 publications

(26 citation statements)

References 23 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3 However, in this study, we used uniform surgical technique, similar IOL type (SN60AT) and placement (within the capsular bag), and standard timing of postoperative refraction. We did not identify any relationship with a particular eye characteristic correlating with higher prediction error for individual formulae; rather, when higher prediction error occurred, it tended to occur across formulae.…”

Section: Discussionmentioning

confidence: 99%

“…All available A-scans were reviewed by a certified echographer to assess quality as described previously; one scan was invalid, and this eye was excluded from analysis. 3 Additional eyes were excluded from analysis for lack of refractive data at the 1 month postoperative visit, diagnosis of glaucoma or suspected glaucoma by the 3-month postoperative visit (which could result in an unpredictable and early myopic shift), or sulcus IOL implantation (which could result in alterations in the effective lens position).…”

Section: Methodsmentioning

confidence: 99%

“…The mean absolute prediction error was 1.8 ± 1.3 diopters (D), with greater error noted in eyes with shorter globe axial length (AL). 3 …”

mentioning

confidence: 99%

“…3–11 Additionally, by the time the postoperative refraction is obtained, rapid growth of an infant’s eye may result in a myopic shift from the predicted postoperative refraction calculated at the time of surgery. 12,13 The Haigis, Hoffer Q, and Holladay formulae have been found to give the lowest prediction error in pediatric or short eyes with a globe AL of less than 22 mm, 14–17 but most studies have very few extremely short eyes (AL <20 mm) for analysis.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Predictability of Intraocular Lens Power Calculation Formulae in Infantile Eyes With Unilateral Congenital Cataract: Results from the Infant Aphakia Treatment Study

VanderVeen

Trivedi

Nizam

et al. 2013

American Journal of Ophthalmology

Self Cite

View full text Add to dashboard Cite

PURPOSE To compare accuracy of intraocular lens (IOL) power calculation formulae in infantile eyes with primary IOL implantation. DESIGN Comparative case series. METHODS The Hoffer Q, Holladay 1, Holladay 2, Sanders-Retzlaff-Kraff (SRK) II, and Sanders-Retzlaff-Kraff theoretic (SRK/T) formulae were used to calculate predicted postoperative refraction for eyes that received primary IOL implantation in the Infant Aphakia Treatment Study. The protocol targeted postoperative hyperopia of +6.0 or +8.0 diopters (D). Eyes were excluded for invalid biometry, lack of refractive data at the specified postoperative visit, diagnosis of glaucoma or suspected glaucoma, or sulcus IOL placement. Actual refraction 1 month after surgery was converted to spherical equivalent and prediction error (predicted refraction – actual refraction) was calculated. Baseline characteristics were analyzed for effect on prediction error for each formula. The main outcome measure was absolute prediction error. RESULTS Forty-three eyes were studied; mean axial length was 18.1 ± 1.1 mm (in 23 eyes, it was <18.0 mm). Average age at surgery was 2.5 ± 1.5 months. Holladay 1 showed the lowest median absolute prediction error (1.2 D); a paired comparison of medians showed clinically similar results using the Holladay 1 and SRK/T formulae (median difference, 0.3 D). Comparison of the mean absolute prediction error showed the lowest values using the SRK/T formula (1.4 ± 1.1 D), followed by the Holladay 1 formula (1.7 ± 1.3 D). Calculations with an optimized constant showed the lowest values and no significant difference between the Holladay 1 and SRK/T formulae (median difference, 0.3 D). Eyes with globe AL of less than 18 mm had the largest mean and median prediction error and absolute prediction error, regardless of the formula used. CONCLUSIONS The Holladay 1 and SRK/T formulae gave equally good results and had the best predictive value for infant eyes.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…The mean absolute prediction error was 1.8 ± 1.3 diopters (D), with greater error noted in eyes with shorter globe axial length (AL). 3 …”

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Predictability of Intraocular Lens Power Calculation Formulae in Infantile Eyes With Unilateral Congenital Cataract: Results from the Infant Aphakia Treatment Study

VanderVeen

Trivedi

Nizam

et al. 2013

American Journal of Ophthalmology

Self Cite

View full text Add to dashboard Cite

show abstract

“…Another arm of the IATS trial assessed the predictability of IOL calculations using the Holladay 1 formula and early postoperative refractive outcomes. Multivariate analyses showed that there was a higher predictive error associated with short axial length (< 18mm) 22 . Overall, 45% of eyes had postoperative refractions within 1D of the targeted refraction, but 41% had a greater than 2D predictive error 21 .…”

Section: Expert Commentarymentioning

confidence: 95%

Evaluating the evidence for and against the use of IOLs in infants and young children

Kumar

Lambert

2016

Expert Review of Medical Devices

View full text Add to dashboard Cite

Summary Congenital cataracts account for 5–20% of childhood blindness worldwide. In the US, the prevalence of visually significant infantile cataracts is anywhere from 3–4 per 10,000 live births. Infantile cataracts need to be removed early in life in order to prevent the onset of deprivation amblyopia. As a result, cataract surgery is usually performed between age 4–8 weeks depending on the laterality and severity of the cataract. Given advances in the field, pediatric cataract surgery is now a safe and effective intervention for infants, but good visual outcomes require occlusion therapy and optical correction. This review will address current perspectives on the use of intraocular lenses to optically correct infants and young children after cataract surgery, as well as novel designs for intraocular lenses and directions for future research.

show abstract

Treatment Outcomes of Monocular Infantile Cataract at 5-Year Follow-up

Repka

2014

JAMA Ophthalmol

View full text Add to dashboard Cite

Predictability of Intraocular Lens Calculation and Early Refractive Status

Cited by 46 publications

References 23 publications

Predictability of Intraocular Lens Power Calculation Formulae in Infantile Eyes With Unilateral Congenital Cataract: Results from the Infant Aphakia Treatment Study

Predictability of Intraocular Lens Power Calculation Formulae in Infantile Eyes With Unilateral Congenital Cataract: Results from the Infant Aphakia Treatment Study

Evaluating the evidence for and against the use of IOLs in infants and young children

Treatment Outcomes of Monocular Infantile Cataract at 5-Year Follow-up

Contact Info

Product

Resources

About