“…It has previously been shown to be an independent prognostic variable, with a negative PR score associated with poor prognosis [ 48 ]. We are not the first to report an association between the PR score and the RS [ [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] ], however the key Oncotype trials did not look at the PR score and therefore this relationship has only been shown by real world data out with clinical trial settings. We have one of the larger datasets showing this association.…”