Precursors in adolescence of adult-onset bipolar disorder

Hiyoshi, Ayako; Sabet, Julia A.; Sjöqvist, Hugo; Melinder, Carren; Brummer, Robert Jan; Montgomery, Scott

doi:10.1016/j.jad.2017.04.071

Cited by 10 publications

(5 citation statements)

References 43 publications

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“…A balanced attributional style for positive events may underlie the lower risk for depressive mood in middle school students who tend to have greater self-esteem than in high school students [74]. Moreover, well-developed stress resilience in late adolescence is associated with a reduced risk for bipolar disorder in adulthood [75]. Furthermore, a study in high-risk adolescents and young adults with depression and suicidal ideation found that increased use of a positive mindset, such as positive reframing, and decreased use of negative cognitive styles, such as self-blame and disengagement, lowered the risk for suicide at baseline and 4 months after the intervention [40].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and associated factors of depression among Korean adolescents

et al. 2019

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This study aimed to identify factors significantly associated with recent depressive mood with respect to health-related behavioral patterns at the individual level, perceived safety in the school environment, and willingness to share concerns with family and social networks. Self-reported responses to questions regarding recent feelings of depression, health-related behaviors in physical, psychological, and spiritual subdomains, school refusal and perceived safety at school, and perceived social support were obtained from 1,991 in-school adolescents (mean [SD] age = 15.3 [1.7] years; male/female = 936/1055). Multivariate logistic regression analyses were used to identify explanatory factors significantly associated with recent depression, defined as feelings of sadness or hopelessness for more than 2 weeks (during the last 12 months) that interfered with everyday functioning. Of the 1,991 students, 271 (13.6%) reported recent depression. Multivariate logistic regression analyses revealed higher odds of recent depression in adolescents with frequent thoughts of school refusal (odds ratio [95% confidence interval] = 3.25 [2.44–4.32]) and those who engaged in regular physical exercise (1.57 [1.19–2.07]), whereas a positive mindset (0.65 [0.49–0.86]), perceived safety at school (0.62 [0.47–0.82]), and perceived social support from one’s mother (0.54 [0.40–0.72]) were associated with lower odds of recent depression. Taken together, our findings suggest that parents and teachers should talk regularly with adolescents about recent life (dis)satisfaction and stressors, particularly when they report frequent thoughts of school refusal. Perceived social support would increase perceived safety on school grounds and make it easier for teenagers to share their concerns with parents, thereby reducing the risk for depressive symptoms. School-based programs that promote a positive mindset would be helpful in preparing students for the challenges of adulthood.

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Section: Discussionmentioning

confidence: 99%

Prevalence and associated factors of depression among Korean adolescents

et al. 2019

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“…Therefore, those with AD may expect a greater disease burden in later adulthood as indicated by their, on average, lower stress resilience. Using the same measure of stress resilience, it has been demonstrated that low resilience in adolescence is associated with a raised risk of adult‐onset depression, anxiety and bipolar disorder, as well as with pharmaceutical treatment for anxiety or depression in middle age, indicating a long‐term association of stress resilience with mental health.…”

Section: Discussionmentioning

confidence: 99%

Atopic dermatitis, educational attainment and psychological functioning: a national cohort study

et al. 2018

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“…Data from a Swedish conscripts study, including 362 patients who developed SZ and 108 patients who developed BD, also found no association between IQ and risk for BD, but a linear relationship between IQ and risk of SZ . Yet a more recent study of n = 213 693 Swedish conscripts found that lower risk for BD (n = 1495) was associated with higher cognitive functioning, as defined by spatial recognition, general knowledge and linguistic understanding, in late adolescence . In contrast, a large study of 195 191 Finnish conscripts found that both high arithmetic reasoning and low visuospatial reasoning increased the risk of developing BD (n = 100) in the same cohort of patients …”

Section: Trajectory Of Cognitive Functioning In Bdmentioning

confidence: 93%

“…10 Yet a more recent study of n = 213 693 Swedish conscripts found that lower risk for BD (n = 1495) was associated with higher cognitive functioning, as defined by spatial recognition, general knowledge and linguistic understanding, in late adolescence. 11 In contrast, a large study of 195 191 Finnish conscripts found that both high arithmetic reasoning and low visuospatial reasoning increased the risk of developing BD (n = 100) in the same cohort of patients. 12 Other evidence suggests that early developmental and school delays may be associated with later development of BD, especially a more severe illness phenotype (psychosis, early onset), though these delays may not be due to cognitive deficits per se.…”

Section: Cognitive Functioning Pre-onset and In Cohorts At Familialmentioning

confidence: 94%

Current understandings of the trajectory and emerging correlates of cognitive impairment in bipolar disorder: An overview of evidence

et al. 2019

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Objectives Cognitive dysfunction affects a significant proportion of people with bipolar disorder (BD), but the cause, trajectory and correlates of such dysfunction remains unclear. Increased understanding of these factors is required to progress treatment development for this symptom dimension. Methods This paper provides a critical overview of the literature concerning the trajectories and emerging correlates of cognitive functioning in BD. It is a narrative review in which we provide a qualitative synthesis of current evidence concerning clinical, molecular, neural and lifestyle correlates of cognitive impairment in BD across the lifespan (in premorbid, prodromal, early onset, post‐onset, elderly cohorts). Results There is emerging evidence of empirical links between cognitive impairment and an increased inflammatory state, brain structural abnormalities and reduced neuroprotection in BD. However, evidence regarding the progressive nature of cognitive impairment is mixed, since consensus between different cross‐sectional data is lacking and does not align to the outcomes of the limited longitudinal studies available. Increased recognition of cognitive heterogeneity in BD may help to explain some inconsistencies in the extant literature. Conclusions Large, longitudinally focussed studies of cognition and its covariation alongside biological and lifestyle factors are required to better define cognitive trajectories in BD, and eventually pave the way for the application of a precision medicine approach for individual patients in clinical practice.

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Precursors in adolescence of adult-onset bipolar disorder

Cited by 10 publications

References 43 publications

Prevalence and associated factors of depression among Korean adolescents

Prevalence and associated factors of depression among Korean adolescents

Atopic dermatitis, educational attainment and psychological functioning: a national cohort study

Current understandings of the trajectory and emerging correlates of cognitive impairment in bipolar disorder: An overview of evidence

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