Abstract:This study aimed to evaluate the oral acute and sub chronic toxicity of Quassia amara (Q. amara) extract. For the acute toxicity study, six male and six female rats received 2000 and 5000 mg/kg Q. amara extract. Rats were observed for 14 days; after sacrifice, liver, kidneys, lung, spleen and heart were submitted to macroscopic analysis. No death occurred and just the liver presented significant difference compared to the control group. For subchronic toxicity, eight groups of 6 male and 6 female rats received… Show more
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