Preclinical Study of Pulsed Field Ablation of Difficult Ventricular Targets: Intracavitary Mobile Structures, Interventricular Septum, and Left Ventricular Free Wall
Moritz Nies,
Keita Watanabe,
Iwanari Kawamura
et al.
Abstract:Background:
- Endocardial catheter-based pulsed field ablation (PFA) of the ventricular myocardium is promising. However, little is known about PFA's ability to target intracavitary structures, epicardium, and ways to achieve transmural lesions across thick ventricular tissue.
Methods:
- A lattice-tip catheter was used to deliver biphasic monopolar PFA to swine ventricles under general anesthesia, with electroanatomical mapping, fluoroscopy and intracar… Show more
“…In pre-clinical studies, it showed promising results for ventricular tissue treatment. 4 , 5 However, there are no clinical studies reported for ventricular tachycardia (VT) ablation. 6…”
“…In pre-clinical studies, it showed promising results for ventricular tissue treatment. 4 , 5 However, there are no clinical studies reported for ventricular tachycardia (VT) ablation. 6…”
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