Precision prognosis of colorectal cancer: a multi-tiered model integrating microsatellite instability genes and clinical parameters
Yonghong Wang,
Ke Liu,
Wanbin He
et al.
Abstract:BackgroundPrognostic assessment for colorectal cancer (CRC) displays substantial heterogeneity, as reliance solely on traditional TNM staging falls short of achieving precise individualized predictions. The integration of diverse biological information sources holds the potential to enhance prognostic accuracy.ObjectiveTo establish a comprehensive multi-tiered precision prognostic evaluation system for CRC by amalgamating gene expression profiles, clinical characteristics, and tumor microsatellite instability … Show more
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