Precision Culture Scaling to Establish High‐Throughput Vasculogenesis Models
Nicholas R. Dennison,
Maximilian Fusenig,
Lisa Grönnert
et al.
Abstract:Hydrogel‐based 3D cell cultures can recapitulate (patho)physiological phenomena ex vivo. However, due to their complex multifactorial regulation, adapting these tissue and disease models for high‐throughput screening workflows remains challenging. In this study, a new Precision Culture Scaling (PCS‐X) methodology combines statistical techniques (Design of Experiment and Multiple Linear Regression) with automated, parallelized experiments and analyses to customize hydrogel‐based vasculogenesis cultures using hu… Show more
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