We study quantum fields on an arbitrary, rigid background with boundary. We derive the action for a scalar in the holographic basis that separates the boundary and bulk degrees of freedom. From this holographic action, a relation between Dirichlet and Neumann propagators valid for any background is obtained. As an application in a warped background, we derive an exact formula for the flux of bulk modes emitted from the boundary. We also derive the holographic action in the presence of two boundaries. Integrating out free bulk modes, we derive a formula for the Casimir pressure on a (d − 1)-brane depending only on the boundary-to-bulk propagators. In AdS 2 we find that the quantum force pushes a point particle toward the AdS 2 boundary. In higher dimensional AdS d+1 the quantum pressure amounts to a detuning of the brane tension, which gets renormalized for even d.We evaluate the one-loop boundary effective action in the presence of interactions by means of the heat kernel expansion. We integrate out a heavy scalar fluctuation with scalar interactions in AdS d+1 , obtaining the long-distance effective Lagrangian encoding loopgenerated boundary-localized operators. We integrate out nonabelian vector fluctuations in AdS 4,5,6 and obtain the associated holographic Yang-Mills β functions. Turning to the expanding patch of dS, following recent proposals, we provide a boundary effective action generating the perturbative cosmological correlators by analytically continuing from dS to EAdS. We obtain the "cosmological" heat kernel coefficients in the scalar case and work out the divergent part of the dS 4 effective action which renormalizes the cosmological correlators. More developments are needed to extract all one-loop information from the cosmological effective action.