Precise localisation of a sentinel lymph node in a rare drainage region with SPECT/MRI using interstitial injection of 99mTc-nanocolloid and superparamagnetic iron oxide

Maza, Sofiane; Taupitz, Matthias; Wegner, Thorsten; Muehler, Matthias R; Zander, Andreas; Munz, Dieter L.

doi:10.1007/s00259-004-1660-4

Cited by 6 publications

(3 citation statements)

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“…The importance of this finding is that metastasis here represents locoregional disease and not systemic metastasis. The paravertebral location of such a SLN was recently confirmed in one patient using fused lymphoscintigraphy SPECT and MRI after the interstitial injection of superparamagnetic iron oxide around the melanoma biopsy site [29]. The authors of this report also used 18F-FDG PET in the patient to screen the paravertebral SLN for metastatic disease as an alternative to SLN biopsy that would have been technically difficult with the SLN in this location although it must be accepted that PET will not be positive in micrometastatic disease and is not recommended for routine screening in early stage melanoma [30,31].…”

Section: Clinical Implications Of Lymphatic Drainage Patternsmentioning

confidence: 89%

Lymphatic Drainage in Patients with Primary Cutaneous Melanoma - the Role of Lymphoscintigraphy in Sentinel Lymph Node Biopsy

Uren¹,

Thompson²,

Howman‐Giles³

et al. 2006

CMIR

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Lymphatic drainage of the skin is highly variable from patient to patient and unexpected patterns of lymph drainage are not uncommon. Drainage can occur from the skin of the back through the posterior body wall to nodes in the retro-peritoneal, paravertebral and para-aortic areas. Drainage from the skin of the back to nodes in the triangular intermuscular space occurs in 10% of back melanomas and drainage from the back over the shoulders to SLNs in the neck is seen in 20% of patients. In the head and neck lymph drainage can occur up the neck from the base to nodes in the occipital and upper cervical regions and drainage can occur from high on the scalp directly to nodes in the supraclavicular fossa completely bypassing nodes higher in the neck. Lymphatic drainage is common across the midline to contralateral SLNs and interval nodes are seen as SLNs in 7% of patients with melanoma.

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Section: Clinical Implications Of Lymphatic Drainage Patternsmentioning

confidence: 89%

Lymphatic Drainage in Patients with Primary Cutaneous Melanoma - the Role of Lymphoscintigraphy in Sentinel Lymph Node Biopsy

Uren¹,

Thompson²,

Howman‐Giles³

et al. 2006

CMIR

View full text Add to dashboard Cite

show abstract

“…For an optimal diagnostic procedure and subsequent treatment, it is furthermore important to accurately pinpoint anatomically the position of the imaging agent. 2 This can be accomplished through multimodality imaging by use of both single-photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). 3 Merging images of SPECT and MRI combines the high sensitivity of SPECT with the anatomical information of MRI.…”

Section: Introductionmentioning

confidence: 99%

“…3 Merging images of SPECT and MRI combines the high sensitivity of SPECT with the anatomical information of MRI. 2 However, at this moment, no imaging agents have been designed that can be visualized with both SPECT and MRI. In order to achieve multimodality imaging with a single agent, both radionuclides and MRI contrast agents have to be combined in one targeted vehicle.…”

Section: Introductionmentioning

confidence: 99%