Precise ligand engineering of Ir(III)‐based photosensitizer with aggregation‐induced emission for image‐guided photodynamic therapy
Jialin Tong,
Ao Liu,
Shanshan Huang
et al.
Abstract:Photodynamic therapy (PDT), which relies on the production of reactive oxygen species (ROS) induced by a photosensitizer to kill cancer cells, has become a non‐invasive approach to combat cancer. However, the conventional aggregation‐caused quenching effect, as well as the low ROS generation ability of photosensitizers, restrict their biological applications. In this work, a new Ir(III) complex with a dendritic ligand has been strategically designed and synthesized by ingenious modification of the ancillary li… Show more
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