Precipitation of methionine and ethyl cellulose in carbon dioxide + ethanol + acetic acid systems at high pressures: Phase equilibrium data for the GAS antisolvent process

Phase Equilibrium and Thermodynamic Modeling of 2-Methyltetrahydrofuran-3-one, Carbon Dioxide, and Lauric Acid Systems

“…The importance of these results is highlighted since, based on the experimental phase equilibrium values obtained, it is possible to select appropriate reaction parameters (temperature, pressure, CO 2 content, and concentration of lauric acid in the solvent) for an esterification reaction catalyzed by enzymes. This considers the availability of substrates in a homogeneous solution and using an immobilized enzyme, such as lipase, more specifically Novozym 435, as a biocatalyst. ,, …”

“…This increase is determined by the types of molecules present and the forces between them . When temperature increases, the more volatile compound (CO 2 ) expands faster than MeTHF-3-one and lauric acid, requiring greater pressure to achieve complete solubilization. ,,,, …”

“…Experimental phase equilibrium measurements for the systems investigated were carried out in a variable-volume cell with visualization capability, following the synthetic visual method. It is important to highlight that the experimental unit and the procedure employed in this work have been validated in previous studies and applied to different systems. ,− Briefly, the procedure involves preparing the sample, assembling the equilibrium visualization cell, and performing visual analysis to obtain the data (Figure ). The apparatus consists of a high-pressure balance cell with variable volume and two sapphire windows.…”