Precipitation of aqueous transition metals in particulate matter during the dithiothreitol (DTT) oxidative potential assay

Abstract

Transition metals in particulate matter (PM) are hypothesized to have enhanced toxicity based on their oxidative potential (OP). The acellular dithiothreitol (DTT) assay is widely used to measure the OP...

Experimental factors influencing the bioaccessibility and the oxidative potential of transition metals from welding fumes

“…Experimentally, they show that less than 10% of the total Mn is in the precipitated form, when the total Mn concentration is less than or equal to 100 mmol L −1 , suggesting a slow kinetics of precipitation. In a recent study, Yalamanchili et al (2022) 81 suggested that under the same conditions the formation of the MnHPO 4 (s) precipitate may not reach equilibrium aer 40 min and could continue to precipitate beyond this time. In our study, this implies that the precipitation of MnHPO 4 (s) can continue in the extracted solution aer ltration.…”

Variability of fine Particulate Matter (PM 1.0 and PM 2.5 ) and its oxidative Potential at different locations in the Northern part of India

“…Among acellular assays, the dithiothreitol (DTT) assay is one of the most commonly used to evaluate the OP of PM (Cui et al, 2023;Yalamanchili et al, 2022;Jiang et al, 2019). It measures the loss of DTT over time when exposed to a PM sample.…”