Precipitation dynamics of surrogate respiratory sessile droplets leading to possible fomites

Rasheed, Abdur; Sharma, Shubham; Kabi, Prasenjit; Saha, Abhishek; Chaudhuri, Swetaprovo; Basu, Saptarshi

doi:10.1016/j.jcis.2021.04.128

Cited by 31 publications

(33 citation statements)

References 83 publications

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“…The optical profilometry data of the dried droplet shows a ring deposit with a ring thickness of ~3-4 μm(refer to FigureS6 in supplementary information). As a result of supersaturation near the rim of the droplet, the onset of crystallization always occurs from the droplet's rim, which acts as a nucleus, and thereby, there is sustained growth of crystals connected to the saturated solution that propagates to the center [9] (Refer to Video 1 in the supplementary information, Figure 2 (a)).Crystallization can start anywhere from the rim (as it is an instability), and there is no control over it with the natural evaporation of the droplets.…”

Section: Spatio-temporal Control Of Crystallizationmentioning

confidence: 99%

“…The formation and growth of dendritic crystals depend on competition between solvent loss (which increases the concentration of salt) and diffusion of salt ions towards the leading edge of the tip (which reduces the concentration of salt in solution) [9]. With the natural evaporation of the droplet, there is no control over the length, shape, or dynamics of crystallization.…”

Section: Multiscale Dendritic Patternsmentioning

confidence: 99%

“…The flow inside the droplet is measured using μ-PIV. The flow inside an SRF droplet (Case 1 in this chapter) was analyzed by Abdur et al [9]. Flow is visualized in the SRF droplet by seeding fluorescent particles of 860 nmprocured from Thermo Fischer (refer to Video 6).…”

Section: Flow Dynamics Inside Droplet Under the Influence Of Vapor Mediationmentioning

confidence: 99%

“…It is The copyright holder for this preprint this version posted June 18, 2021. ; https://doi.org/10.1101/2021.06. 18.448992 doi: bioRxiv preprint bio-fluid droplet, the competition between capillary flows driven by continuity and solutal Marangoni flows driven by surface tension gradients (due to differential evaporation of the components) determines the fluid flowinside a droplet [9]. Researchers have observed suppression of the coffee ring effect due to protein adsorption on the surface of the particles in protein droplets containing suspended polystyrene particles [10].…”

Section: Introductionmentioning

confidence: 99%

“…CC-BY-NC-ND 4.0 International license made available under a (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is The copyright holder for this preprint this version posted June 18, 2021. ; https://doi.org/10.1101/2021.06.18.448992 doi: bioRxiv preprint droplets [9,10]. Bacterial motility in these droplets is key to its navagation [24], biofilm formation [25], and self-assembly [26] and is crucial for its survival in the dried precipitates [27].…”

Section: Introductionmentioning

confidence: 99%

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Vapor mediation as a tool to control micro-nano scale dendritic crystallization and preferential bacterial distribution in drying respiratory droplets

Hegde

Chatterjee

Rasheed

et al. 2021

Preprint

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Deposits of biofluid droplets on surfaces (such as respiratory droplets formed during an expiratory event fallen on surfaces) are composed of the water based salt protein solution that may also contain an infection (bacterial/viral). The final patterns of the deposit formed are dictated by the composition of the fluid and flow dynamics within the droplet. This work reports the spatio temporal, topological regulation of deposits of respiratory fluid droplets and control of motility of bacteria by tweaking flow inside droplets using non contact vapor mediated interactions. When evaporated on a glass surface, respiratory droplets form haphazard multiscale dendritic, cruciform shaped precipitates using vapor mediation as a tool to control these deposits at the level of nano, micro, millimeter scales. We morphologically control dendrite orientation, size and subsequently suppress cruciform-shaped crystals. The nucleation sites are controlled via preferential transfer of solutes in the droplets; thus, achieving control over crystal occurrence and growth dynamics. The active living matter like bacteria is also preferentially segregated with controlled motility without attenuation of its viability and pathogenesis. For the first time, we have experimentally presented a proof of concept to control the motion of live active matter like bacteria in a near nonintrusive manner. The methodology can have ramifications in biomedical applications like disease detection, controlling bacterial motility, and bacterial segregation.

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Section: Spatio-temporal Control Of Crystallizationmentioning

confidence: 99%

Section: Multiscale Dendritic Patternsmentioning

confidence: 99%

Section: Flow Dynamics Inside Droplet Under the Influence Of Vapor Mediationmentioning

confidence: 99%