PRECICE intramedullary limb lengthening system

Paley, Dror

doi:10.1586/17434440.2015.1005604

Cited by 169 publications

(163 citation statements)

References 31 publications

Supporting

Mentioning

140

Contrasting

Unclassified

Order By: Relevance

“…Phenix® nails (Phenix Medical, France), available in 2009, are magnetically actuated lengthening nails [2]. PRECICE® (Nuvasive, Aliso Viego, CA, USA), another magnetically actuated lengthening nail, was launched in 2011 [20].…”

Section: Internal Lengthening Rodsmentioning

confidence: 99%

“…ISKD and Albizzia/Guichet nails work by an interlocking ratchet mechanism that translates limb-twisting movementsperformed by the patient or caregiver and often associated with excruciating pain [20]-into forward slippage of the nail male portion. Approximately 3-9°pivoting movements around the soft regenerate are required for ISKD and 20°for Albizzia/Guichet nails [4,21], neither of which is commercially available in the USA.…”

Section: Internal Lengthening Rodsmentioning

confidence: 99%

“…Phenix and PRECICE nails are magnetically motorised rods capable of lengthening and shortening long bones [20,25]. Rod-length increase or decrease occurs in response to a portable external remote controller (ERC) placed superficially on the skin [31].…”

Section: Internal Lengthening Rodsmentioning

confidence: 99%

“…Likewise, shortening may help ameliorate other distraction-related complications, such as joint subluxation and progressive soft tissue contractures. Based on the compression concept, Paley reported a case of simultaneous ankle arthrodesis and distal tibia lengthening using PRECICE nail [20].…”

Section: Compressionmentioning

confidence: 99%

“…Intra-operative correction of mild, pre-existent angular deformities can be attempted with internal lengthening rods [20,37,38]. External fixator should be applied to maintain the corrected position until the nail is fully seated [26].…”

Section: Deformity Correctionmentioning

confidence: 99%

See 4 more Smart Citations

Use of internal lengthening nails in post-traumatic sequelae

Alrabai

Gesheff

Conway

2017

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

External fixators are a well-established modality for treating fractures with bone defects, leg-length discrepancy, malunion, nonunion and other post-traumatic consequences. However, use of internal lengthening rods has remarkably increased recently for post-traumatic conditions. The main advantage of internal lengthening rods is eliminating pin-site complications. Internal lengthening rods are also associated with less pain. Motorised internal lengthening rods show promising performance in post-traumatic cases. Rigorous pre-operative planning is paramount to reducing lengthening-related complications. Certain types of internal lengthening rods offer bidirectional movement capability. Nail mechanism malfunction is a possibility with all kinds of nails. Direct doctor supervision is required, especially in the initial stages while the nail is lengthening. Internal lengthening nails are not as stiff as regular nails, with intricate internal mechanisms that can be broken under inattentive weightbearing activities. Preliminary positive outcomes indicate the role of internal lengthening rods in treating posttraumatic problems of leg-length discrepancy, malunion and nonunion.

show abstract

Section: Internal Lengthening Rodsmentioning

confidence: 99%

Section: Internal Lengthening Rodsmentioning

confidence: 99%

Section: Internal Lengthening Rodsmentioning

confidence: 99%

Section: Compressionmentioning

confidence: 99%

Section: Deformity Correctionmentioning

confidence: 99%

See 3 more Smart Citations

Use of internal lengthening nails in post-traumatic sequelae

Alrabai

Gesheff

Conway

2017

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

Achondroplasia: Development, pathogenesis, and therapy

Ornitz

Legeai-Mallet

2017

Developmental Dynamics

169

177

View full text Add to dashboard Cite

Autosomal dominant mutations in Fibroblast Growth Factor Receptor 3 (FGFR3) cause Achondroplasia (Ach), the most common form of dwarfism in humans, and related chondrodysplasia syndromes that include Hypochondroplasia (Hch), Severe Achondroplasia with Developmental Delay and Acanthosis Nigricans (SADDAN), and Thanatophoric dysplasia (TD). FGFR3 is expressed in chondrocytes and mature osteoblasts where it functions to regulate bone growth. Analysis of the mutations in FGFR3 revealed increased signaling through a combination of mechanisms that include stabilization of the receptor, enhanced dimerization, and enhanced tyrosine kinase activity. Paradoxically, increased FGFR3 signaling profoundly suppresses proliferation and maturation of growth plate chondrocytes resulting in decreased growth plate size, reduced trabecular bone volume, and resulting decreased bone elongation. In this review we discuss the molecular mechanisms that regulate growth plate chondrocytes, the pathogenesis of Ach, and therapeutic approaches that are being evaluated to improve endochondral bone growth in people with Ach and related conditions.

show abstract

Multi‐Axis Fatigue Experimentation System of Intramedullary Implants for Femur and Tibia

Kanerva

Pärnänen

Jokinen

et al. 2019

Journal Orthopaedic Research

View full text Add to dashboard Cite

Current designs of leg-lengthening implants have faced serious failures due to inadequacies in the mechanical design. The failure typically is the result of fatigue induced by a combined loading condition with axial and shear components acting in the tubular body of the implant. One of the reasons leading to the failure is improper verification testing for the design of the fatigue limit. The current test standards for pre-clinical design phases of nail implants are relatively straightforward and widely accepted yet cannot produce the three-dimensional stress state representative of the anticipated operation in a patient during the consolidation phase. This work introduces a major improvement toward a method for verifying fatigue life of tubular as well as solid implants under combined torque, axial load, and bending. The report describes a new loading fixture, a calibration method, and compares the qualification results of finite element simulation analyses and experimental measurements during cyclic loading tests. The findings state that the fixture produces controlled multi-axial loadings to study varied osteotomy locations, quasi-static strength and fatigue of intramedullary implants at an intermediate, 2 Hz, cycle rate.

show abstract

PRECICE intramedullary limb lengthening system

Cited by 169 publications

References 31 publications

Use of internal lengthening nails in post-traumatic sequelae

Use of internal lengthening nails in post-traumatic sequelae

Achondroplasia: Development, pathogenesis, and therapy

Multi‐Axis Fatigue Experimentation System of Intramedullary Implants for Femur and Tibia

Contact Info

Product

Resources

About