Prealbumina, precalicreína e protrombina na forma hepatesplênica da esquistossomose: catabolismo aumentado de proteínas da coagulação?

Manoukian, Nora; Borges, Durval Rosa

doi:10.1590/s0036-46651984000500001

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Kinins and Their Implication In Protozoan And Parasite In1

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2020

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Cited by 10 publications

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“…Clinical data suggest the participation of kinins in schistosomiasis pathophysiology. PPK and HMWK concentrations were lower in hepatosplenic schistosomiasis patients, when compared with the control group [ 173 , 174 ]. A therapeutic approach employing a short human kininogen insertion into S. japonicum glutathione S-transferases, ameliorated their biological activity, and inhibited human umbilical vein endothelial cell proliferation [ 175 ].…”

Section: Kinins and Their Implication In Protozoan And Parasite Inmentioning

confidence: 99%

Kinins and Their Receptors in Infectious Diseases

2020

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Kinins and their receptors have been implicated in a series of pathological alterations, representing attractive pharmacological targets for several diseases. The present review article aims to discuss the role of the kinin system in infectious diseases. Literature data provides compelling evidence about the participation of kinins in infections caused by diverse agents, including viral, bacterial, fungal, protozoan, and helminth-related ills. It is tempting to propose that modulation of kinin actions and production might be an adjuvant strategy for management of infection-related complications.

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Section: Kinins and Their Implication In Protozoan And Parasite Inmentioning

confidence: 99%