Pre-pregnancy body mass index and parent and teacher-reported behavioral outcomes among offspring in childhood

Parker, Samantha E.; Carlson, Jeffrey M.; Kebede, Nehemiah; Werler, Martha M.; Janulewicz, Patricia

doi:10.1016/j.ntt.2021.107049

Cited by 5 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All studies assessed the exposure to maternal prepregnant overweight and obesity, while six studies also investigated the exposure to fathers. All but 8 studies [ 29 , 30 , 34 , 37 , 38 , 41 , 53 , 54 ] defined weight groups according to World Health Organization categories(WHO).4 articles [ 24 , 32 , 35 , 38 ] collapsed underweight and normal weight into the same category (BMI < 24.99), which was analyzed collectively as normal weight,9 studies [ 24 , 32 , 39 , 40 , 46 , 49 – 51 , 54 ] further divided obesity into Obese Class I, II and III (or II/III), 3 articles [ 44 , 45 , 53 ] grouped overweight and obese mothers together. Thus, these were analyzed only as a combined obese and overweight category.…”

Section: Resultsmentioning

confidence: 99%

Effects of parental overweight and obesity on offspring’s mental health: A meta-analysis of observational studies

Zhang

Lin

Liu³

et al. 2022

PLoS ONE

View full text Add to dashboard Cite

Background Children of parents who were overweight/obese prior to pregnancy face a variety of neurodevelopmental challenges. The goal of this meta-analysis is to compile evidence about the impact of parental overweight/obesity on their children’s mental health. Methods The databases Cochrane Library, EMBASE, Pubmed, PsycINFO, and Web of Science were searched until May 2022. The pooled effect size was calculated using the fixed and random effect models. We also performed I2 index, subgroup analyses, sensitivity analyses, quality assessment, and publication bias analysis. The protocol was registered on the PROSPERO database (CRD42022334408). Results For maternal exposure (35 studies), both maternal overweight [OR 1.14 (95% CI 1.10,1.18)] and maternal obesity [OR 1.39 (95% CI (1.33, 1.45)] were significantly associated with offspring’s mental disorders. Maternal pre-pregnancy overweight/obesity increased the risk of attention-deficit/hyperactivity disorder (ADHD) [OR 1.55 (95% CI 1.42,1.70)], autism spectrum disorder (ASD) [OR 1.37 (95% CI 1.22,1.55)], cognitive/intellectual delay [OR 1.40 (95% CI 1.21,1.63)], behavioral problems [OR 1.50 (95% CI 1.35,1.66)] and other mental diseases [OR 1.30 (95% CI 1.23,1.37)]. For paternal exposure (6 studies), paternal obesity [OR 1.17 (95% CI 1.06, 1.30)] but not overweight [OR 1.03 (95% CI 0.95,1.11)] was significantly associated with offspring’s mental disorders. Conclusions Parental overweight/obesity might have negative consequences on offspring’s mental health and pre-pregnancy weight control is advised.

show abstract

Section: Resultsmentioning

confidence: 99%

Effects of parental overweight and obesity on offspring’s mental health: A meta-analysis of observational studies

Zhang

Lin

Liu³

et al. 2022

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Despite several studies examining the association between pre-pregnancy BMI and adverse physical and neurodevelopmental outcomes [15][16][17][18], studies on the association between pre-pregnancy BMI and offspring behavioural problems are limited, and the findings are inconsistent. While some studies have reported an increased risk for emotional and behavioural outcomes in the offspring of mothers who are underweight, overweight, or obese [19][20][21], others have found little or no evidence of associations [22][23][24]. Similarly, we are only aware of two studies that examined the association between gestational weight gain and child emotional and behavioural problems, with one reporting a positive association between excessive gestational weight gain and child behaviour [25], while the other found no associations [26].…”

Section: Introductionmentioning

confidence: 85%

“…Most existing studies reporting the impact of pre-pregnancy BMI and gestational weight gain on offspring behavioural problems were based on small sample sizes [19,20,25,26], examined the associations at one time-point only [20][21][22][23][24][25][26], and did not consistently account for important confounding factors, such as maternal education, smoking, and psychopathology [19,21,22,25]. In this study, we aimed to address these gaps in the literature by examining the associations at five developmental periods ranging from age 3 to 16 years.…”

Section: Introductionmentioning

confidence: 99%

Maternal Pregnancy and Pre-Pregnancy Weight and Behavioural Outcomes in Children

Dachew,

Adane,

Alati

2024

Behavioral Sciences

View full text Add to dashboard Cite

Reported associations of pre-pregnancy weight and/or gestational weight gain with offspring behavioural outcomes are inconsistent. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), this study aimed to examine these associations at five developmental stages between the ages of 3 and 16. Over 6800 mother–offspring pairs at age 3 and 3925 pairs at age 16 were included. Pre-pregnancy underweight was associated with a 22% increased risk of total behavioural difficulties (OR = 1.22, 95% CI 1.02–1.45). In separate analyses using the SDQ subscales, pre-pregnancy underweight was linked to a 37% (OR = 1.37, 95% CI 1.14–1.65) and 33% (OR = 1.33, 95% CI 1.01–1.76) increased risk of emotional symptoms and prosocial behaviour problems over time, respectively. While pre-pregnancy overweight was associated with an 11% (OR = 1.11, 95% CI 1.03–1.20) and 18% (OR = 1.18, 95% CI 1.03–1.36) increased risk of conduct and peer relationship problems, respectively, pregnancy obesity was associated with a 43% increased risk of emotional problems (OR = 1.43, 95% CI 1.16–1.77). We found no evidence of associations between gestational weight gain and child behaviour except for a reduced risk in prosocial behaviour problems (OR = 0.82, 95% CI 0.70–0.96). Our findings provide insights into the link between preconception BMI and child behaviour, underscoring the necessity for further research to validate these associations and elucidate underlying mechanisms.

show abstract

“…Previous studies have shown that children born of mothers who are obese before pregnancy have an increased risk of behavioral problems compared to mothers with normal weight before pregnancy [ 30 ]. MENTING MD et al found that maternal pre-pregnancy overweight/obesity was associated with an increased risk of children’s total behavioral problems and hyperactivity/inattention problems but not significantly associated with emotional, conduct and peer relationship problems in children [ 31 ], which was different from our findings.…”

Section: Discussionmentioning

confidence: 99%

Non-Linear and Sex-Specific Effect of Maternal Pre-Pregnancy BMI on Emotional and Behavioral Development of Preschool Children: A Population-Based Cohort Study

Hao

et al. 2022

IJERPH

View full text Add to dashboard Cite

(1) Background: The aim was to examine the non-linear and sex-specific outcomes of maternal pre-pregnancy BMI on emotional and behavioral development of preschool children; (2) Methods: This study was based on the China-Anhui Birth Cohort (C-ABCS), including 3648 mother–child pairs. Maternal pre-pregnancy BMI was calculated from the maternal pre-pregnancy height and weight measured at the first antenatal checkup. Main caregivers completed the Strengths and Difficulties Questionnaire (SDQ) to assess children’s preschool emotional and behavioral development. A restricted cubic spline model was drawn using Stata version 15.1 to analyze the association between maternal pre-pregnancy BMI and preschoolers’ SDQ scores by sex; (3) Results: Among boys, maternal pre-pregnancy underweight was associated with the increased risk of conduct problems and pro-social behaviors, and pre-pregnancy overweight/obesity related with the increased risk of peer problems. Interestingly, when maternal pre-pregnancy BMI was between 18.50 kg/m2 and 18.67 kg/m2, boys had the increased risk of conduct problems. When pre-pregnancy BMI was between 18.50 kg/m2 and 19.57 kg/m2, boys had the increased risk of pro-social problems. No significant associations were observed; (4) Conclusions: A non-linear effect of maternal pre-pregnancy BMI on emotional and behavioral development has been found in preschool boys. In particular, pre-pregnancy normal weight may still affect boys’ emotional and behavioral development.

show abstract

Pre-pregnancy body mass index and parent and teacher-reported behavioral outcomes among offspring in childhood

Cited by 5 publications

References 46 publications

Effects of parental overweight and obesity on offspring’s mental health: A meta-analysis of observational studies

Effects of parental overweight and obesity on offspring’s mental health: A meta-analysis of observational studies

Maternal Pregnancy and Pre-Pregnancy Weight and Behavioural Outcomes in Children

Non-Linear and Sex-Specific Effect of Maternal Pre-Pregnancy BMI on Emotional and Behavioral Development of Preschool Children: A Population-Based Cohort Study

Contact Info

Product

Resources

About