Purpose
This study’s impetus is to make a quantitative analysis on the characteristics of chronic idiopathic macular hole (IMH) using spectral-domain optical coherence tomography (OCT).
Methods
IMH persisting for ≥ 1 year confirmed by OCT was defined as chronic IMH. Symptom duration of macular hole for ≤ 6 months and/or macular hole persisting for ≤ 6 months was shown by preoperative OCT, which was defined as acute IMH. OCT parameters were compared between the two groups.
Results
A total of 95 eyes were included in the study, including 16 eyes with chronic IMH and 79 eyes with acute IMH. Statistically significant differences were noted in minimum linear diameter (MLD), hole height (HH), macular hole index (MHI), tractional hole index (THI) and hole form factor (HFF) (p = 0.002, p = 0.002, p = 0.003, p = 0.002, p < 0.001, ANCOVA test, respectively) between the two groups. MLD (OR 0.992, 95% CI from 0.987 to 0.996) and HH (OR 1.012, 95% CI from 1.003 to 1.021) was identified as a factor closely associated with the diagnosis of chronic IMH after logistic regression analysis. The diagnostic model had an area under the receiver operating characteristic (ROC) curve of 0.880 and 95% CI from 0.830 to 0.957, p < 0.001.
Conclusion
Chronic IMH has a larger MLD, smaller HH, MHI, THI, and HFF. MLD and HH is closely correlated with the diagnosis of chronic macular holes, which is easy to apply in clinical practice and does not require complex measurements or calculations.