Pre-operative nutritional serum parameters as predictors of failure after internal fixation in undisplaced intracapsular proximal femur fractures

Bajada, Stefan; Smith, Adam; Morgan, David

doi:10.1016/j.injury.2015.05.001

Cited by 34 publications

(20 citation statements)

References 36 publications

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“…Similarly, other researchers found lower s-alb levels in the hip fracture patients compared to controls 22 . Furthermore, as shown in other studies, low s-alb levels are associated with morbidity and mortality in hip fracture patients 23 . S-alb is a widely used biochemical marker of malnutrition in hip fracture patients, although it could also be attributed to acute phase or immediate response patterns (naturally occurring after trauma) that compromise albumin production 24,25 .…”

Section: Discussionsupporting

confidence: 67%

Evaluation of commonly used nutritional assessment methods in hip fracture patients

Tsagari

Papakitsou

Dionyssiotis

et al. 2017

JFSF

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Section: Discussionsupporting

confidence: 67%

Evaluation of commonly used nutritional assessment methods in hip fracture patients

Tsagari

Papakitsou

Dionyssiotis

et al. 2017

JFSF

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“… 23 The NICE guidelines recommend identifying and treating uncontrolled diabetes as soon as possible to minimize delays before surgery but do not define specific cutoffs for blood glucose prior to surgery ( Table 3 ). 9 …”

Section: Resultsmentioning

confidence: 99%

“… 8 The NICE guidelines are intended to provide evidence-based guidance to promote integrated care for the National Health Service of the United Kingdom. 9 …”

Section: Methodsmentioning

confidence: 99%

Surgical Technical Evidence Review of Hip Fracture Surgery Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery

Siletz

Childers

Faltermeier

et al. 2018

Geriatr Orthop Surg Rehabil

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Background:Enhanced recovery pathways (ERPs) have been shown to improve patient outcomes in a variety of contexts. This review summarizes the evidence and defines a protocol for perioperative care of patients with hip fracture and was conducted for the Agency for Healthcare Research and Quality safety program for improving surgical care and recovery.Study Design:Perioperative care was divided into components or “bins.” For each bin, a semisystematic review of the literature was conducted using MEDLINE with priority given to systematic reviews, meta-analyses, and randomized controlled trials. Observational studies were included when higher levels of evidence were not available. Existing guidelines for perioperative care were also incorporated. For convenience, the components of care that are under the auspices of anesthesia providers will be reported separately. Recommendations for an evidence-based protocol were synthesized based on review of this evidence.Results:Eleven bins were identified. Preoperative risk factor bins included nutrition, diabetes mellitus, tobacco use, and anemia. Perioperative management bins included thromboprophylaxis, timing of surgery, fluid management, drain placement, early mobilization, early alimentation, and discharge criteria/planning.Conclusions:This review provides the evidence basis for an ERP for perioperative care of patients with hip fracture.

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“…Serologic results on admission, including lymphocyte count, creatinine, albumin, and hemoglobin levels, were collated. Creatinine, albumin, and lymphocyte counts have all been linked to the presence of malnutrition and are thus considered to be a potential predictor of poor outcome [16-18].…”

Section: Methodsmentioning

confidence: 99%

C2 Fractures in the Elderly: Single-Center Evaluation of Risk Factors for Mortality

et al. 2019

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Study DesignRetrospective cohort study.PurposeThe aim of this study was to identify features associated with increased mortality risk in traumatic C2 fractures in the elderly, including measures of comorbidity and frailty.Overview of LiteratureC2 fractures in the elderly are of increasing relevance in the setting of an aging global population and have a high mortality rate. Previous analyzes of risk factors for mortality have not included the measures of comorbidity and/or frailty, and no local data have been reported to date.MethodsThis study comprises a retrospective review of 70 patients of age >65 years at Waikato Hospital, New Zealand with traumatic C2 fractures identified on computed tomography between 2010 and 2016. Demographic details, medical history, laboratory results on admission, mechanism of injury, and neurological status on presentation were recorded. Medical comorbidities were also detailed allowing calculation of the Charlson Comorbidity Index (CCI) and the modified Frailty Index (mFI).ResultsThe most common mechanism of injury was a fall from standing height (n=52, 74.3%). Mortality rates were 14.3% (n=10) at day 30, and 35.7% (n=25) at 1 year. Bivariate analysis showed that both CCI and mFI correlated with 1-year mortality rates. Reduced albumin and hemoglobin levels were also associated with 30-day and 1-year mortality rates. Forward stepwise logistic regression models determined CCI and low hemoglobin as predictors of mortality within 30 days, whereas CCI, low albumin, increased age, and female gender predicted mortality at 1 year.ConclusionsThe CCI was a useful tool for predicting mortality at 1 year in the patient cohort. Other variables, including common laboratory markers, can also be used for risk stratification, to initiate timely multidisciplinary management, and prognostic counseling for patients and family members.

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Pre-operative nutritional serum parameters as predictors of failure after internal fixation in undisplaced intracapsular proximal femur fractures

Cited by 34 publications

References 36 publications

Evaluation of commonly used nutritional assessment methods in hip fracture patients

Evaluation of commonly used nutritional assessment methods in hip fracture patients

Surgical Technical Evidence Review of Hip Fracture Surgery Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery

C2 Fractures in the Elderly: Single-Center Evaluation of Risk Factors for Mortality

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