“…Several studies have investigated the factors influencing the outcomes of carpal tunnel release. Worse outcomes of surgery have been associated with preoperative muscle weakness or atrophy (4,7,8), worker's compensation (9,10), predisposing medical conditions (4) including diabetes and thyroid disease (11), heavy or repetitive manual work (12,13), exposure to vibration (14), incorrect diagnosis (15), and incomplete sectioning of the transverse carpal ligament (15). Predictors of favorable surgical outcomes include prominence of paresthesia (rather than numbness or weakness [16]) and favorable response to corticosteroid injection (4,17).…”