Pre-incision infiltration with lidocaine reduces pain and opioid consumption after reduction mammoplasty

Abstract

Preoperative tumescent infiltration with lidocaine results in reduced pain and lower postoperative opioid requirements in the initial hours after reduction mammoplasty.

Does intravenous dexamethasone prevent nausea and vomiting after reduction mammoplasty?

“…Eighty per cent of patients receiving placebo in this study suffered from PONV, which is consistent with similar research in this field (12). Risk factors for PONV include being female, nonsmoking and a past history of PONV or motion sickness (13).…”

Regional block and mexiletine: The effect on pain after cancer breast surgery

“…Subcutaneous infiltration with lidocaine similarly reduced pain after breast surgery. 7 The opioid sparing effect results in less nausea and vomiting, early food intake, and ambulation.…”

Estimated Maximal Safe Dosages of Tumescent Lidocaine

“…The threshold serum concentration for mild lidocaine toxicity (lightheadedness, paresthesias, tinnitus, blurred vision, nystagmus, ataxia, slurred speech, confusion) is 6 μg/mL. [30][31][32] The principal aim of our research was to measure serum lidocaine concentrations as a function of milligram per kilogram dosage of tumescent lidocaine. Our main hypothesis BACKGROUND: Tumescent lidocaine anesthesia consists of subcutaneous injection of relatively large volumes (up to 4 L or more) of dilute lidocaine (≤1 g/L) and epinephrine (≤1 mg/L).…”