Pre-eclampsia is associated with later kidney chronic disease and end-stage renal disease: Systematic review and meta-analysis of observational studies

Ferreira, Raphaela Costa; Fragoso, Marilene Brandão Tenório; Tenório, Micaely Cristina dos Santos; Silva, João Victor Farias; Bueno, Nassib Bezerra; Goulart, Marília Oliveira Fonseca; Oliveira, Alane Cabral Menezes de

doi:10.1016/j.preghy.2020.07.012

Cited by 6 publications

(6 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This results in an increase in soluble fms‐like tyrosine kinase‐1 (sFLT‐1), an antiangiogenic protein which is one of the most recognized factors in the pathophysiology of pre‐eclampsia 16 . sFLT‐1 causes characteristic injuries to the kidney; both podocyte lesions and glomerular endotheliosis, which is a variant of thrombotic microangiopathy 17 . The renal injury usually reverses rapidly following delivery, but still confers an increased risk for end‐stage renal disease and CKD both postnatally and in the longer‐term 17 .…”

Section: Pre‐eclampsiamentioning

confidence: 99%

“…sFLT‐1 causes characteristic injuries to the kidney; both podocyte lesions and glomerular endotheliosis, which is a variant of thrombotic microangiopathy 17 . The renal injury usually reverses rapidly following delivery, but still confers an increased risk for end‐stage renal disease and CKD both postnatally and in the longer‐term 17 . The exact mechanism requires further study 17 .…”

Section: Pre‐eclampsiamentioning

confidence: 99%

“… 17 The renal injury usually reverses rapidly following delivery, but still confers an increased risk for end‐stage renal disease and CKD both postnatally and in the longer‐term. 17 The exact mechanism requires further study. 17 A systematic review and meta‐analysis by Costa Ferriera et al 17 in 2020 found that the probability of developing CKD is 75% higher following pre‐eclampsia (HR 1.82 [95% CI: 1.27–2.62]), and probability of end‐stage renal disease is three‐fold higher (HR 3.01 [95% CI 1.92–4.70]).…”

Section: Pre‐eclampsiamentioning

confidence: 99%

See 2 more Smart Citations

Pregnancy complications and later life women's health

McNestry

Killeen

Crowley

et al. 2023

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

There has been increasing recognition of the association between various pregnancy complications and development of chronic disease in later life. Pregnancy has come to be regarded as a physiological stress test, as the strain it places on a woman's body may reveal underlying predispositions to disease that would otherwise remain hidden for many years. Despite the increasing body of data, there is a lack of awareness among healthcare providers surrounding these risks. We performed a narrative literature review and have summarized the associations between the common pregnancy complications including gestational hypertension, pre-eclampsia, gestational diabetes, placental abruption, spontaneous preterm birth, stillbirth and miscarriage and subsequent development of chronic disease. Hypertensive disorders of pregnancy, spontaneous preterm birth, gestational diabetes, pregnancy loss and placental abruption are all associated with increased risk of various forms of cardiovascular disease.Gestational diabetes, pre-eclampsia, early miscarriage and recurrent miscarriage are associated with increased risk of diabetes mellitus. Pre-eclampsia, stillbirth and recurrent miscarriage are associated with increased risk of venous thromboembolism. Cardiovascular-related morbiditya OR 1.67 (95% ICI: 1.28-2.19) 14 Cerebrovascular morbidity OR 1.83 (95% ICI: 0.79-4.22) 14 Note: Statistics quoted as per reporting study. Abbreviation: OR, odds ratio. a Including coronary artery disease, myocardial infarction, coronary revascularization, peripheral arterial disease, transient ischemic attack, and stroke.

show abstract

Section: Pre‐eclampsiamentioning

confidence: 99%

Section: Pre‐eclampsiamentioning

confidence: 99%

Section: Pre‐eclampsiamentioning

confidence: 99%

See 1 more Smart Citation

Pregnancy complications and later life women's health

McNestry

Killeen

Crowley

et al. 2023

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

“…Certain immunosuppressants like MMF and ACE inhibitors are potentially teratogenic [57, 58]. Among women with CKD, pregnancy risks are substantial, with up to 10-fold higher risk for preeclampsia and 6-fold higher risk for preterm delivery [59, 60]. Pregnancy complications associated with inadequate placentation also increase maternal and newborn risks for cardiovascular morbidity/mortality and progression to kidney failure.…”

Section: Chronic Kidney Disease/end-stage Kidney Disease In Adolescents and Young Adultsmentioning

confidence: 99%

An Interdisciplinary Approach to Optimize the Care of Transitioning Adolescents and Young Adults with CKD

Ferris

Martínez

Velázquez³

et al. 2021

Blood Purif

View full text Add to dashboard Cite

Adolescents and young adults (AYAs) with CKD or end-stage kidney disease (ESKD) have unique medical, dental, psychosocial, neurocognitive, and academic needs and require close interdisciplinary collaboration to optimize their care. The etiology of CKD in AYAs is diverse compared to older adults. With their continuously improved survival, AYAs must start preparation for health-care transition (HCT) from pediatric- to adult-focused health care in the pediatric setting and it must continue at the adult-focused setting, given that their brain maturation and self-management skill acquisition occur until their mid-20s. While the growth and physical maturation of most visible body parts occur before 18 years of age, the prefrontal cortex of the brain, where reasoning, impulse control, and other higher executive functions reside, matures around 25 years of age. The HCT process must be monitored using patient- and caregiver-measuring tools to guide interventions. The HCT process becomes more complex when patients and/or caregivers have a language barrier, different cultural beliefs, or lower literacy levels. In this article, we discuss the unique comorbidities of pediatric-onset CKD/ESKD, provide information for a planned HCT preparation, and suggest interdisciplinary coordination as well as cultural and literacy-appropriate activities to achieve optimal patient outcomes.

show abstract

“…In addition, many but not all studies have suggested women with preeclampsia and normal kidney function have increased risk for later CKD and kidney failure, although absolute risk for kidney failure is under 1% within 20 years. 3 Like CKD, preeclampsia is a health disparity. For Black women, the rate of preeclampsia is 60% higher than for White women, 2 and the former have greater risk of maternal and fetal complications in the peripartum period.…”

mentioning

confidence: 99%