Pre-eclampsia, eclampsia and the thrombotic microangiopathic syndromes of pregnanacy

No Hypertensive Disorder of Pregnancy; No Preeclampsia-eclampsia; No Gestational Hypertension; No Hellp Syndrome. Vascular Disorder of Pregnancy Speaks for All

“…Although the exact mechanism regarding the induction of this disease remains enigmatic, vascular disorder characterized by generalized endothelial damage and vasospasm is a well-known pathology resulting in systemic complications during pregnancy ( 2 – 4 ). Apart from the pathogenesis, there is also uncertainty in its natural course, diagnosis and screening methods ( 3 ).…”

“…Neither hypertensive pregnancy disorders nor the current sub-classifications (chronic hypertension, preeclampsia-eclampsia, gestational hypertension, superimposed preeclampsia on chronic hypertension) is inclusive as these terminologies only partly describe the disease's clinical manifestations. Since endothelial damage is the unifying pathology behind all the clinical manifestations ( 2 – 4 ), vascular disorder of pregnancy (VDP) is a simplified but comprehensive terminology to describe the spectrum of the disease. Although the timing of occurrence varies, all the systemic complications (cardiovascular, renal, hematologic, intracranial, hepatic, pulmonary and uteroplacental) are the consequences of the generalized endothelial vascular damage resulting in vasospasm.…”