Pre-analytical Considerations for Clinical Assays of Circulating Human miRNA-451a for Diagnostic Purposes.
M. Rohan Fernando,
Dinesh S Chandel,
Wesley Tom
et al.
Abstract:Circulating miRNA-451a has recently emerged as an important biomolecule with potential clinical values as a diagnostic marker for several diseases. However, to be used as such, it is critical to accurately assay miRNA-451a in the clinic. Yet, pre-analytical factors that can affect such an error-free clinical assay of miRNA-451a have not been explored. This study aimed at investigating several of these pre-analytical factors that may affect the accurate quantification of miRNA-451a in human blood samples. We in… Show more
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