Pravni Aspekt Urbane Kulture U Srbiji

Modern view on the structure of the vascular extracellular matrix

“…Overall, there are seven types of acid GAGs: strongly sulphated (proteoglycans), strongly sulphated epithelial mucins, weakly sulphated epithelial mucins (sulphomucins), atypical sulphated mucins, carboxylated mucins, sulphated sialomucins and hyaluronic acid. Neutral mucins do not contain reactive groups and are consisted of various hexosamines associated with free hexose groups (26,27).…”

“…Because of their ability to bind cells to the elements of the extracellular matrix, they represent the most important integrative component of the connective tissue. In the vascular wall, especially in the coronary arteries, fibronectin, laminin, entactin, thrombospondin, vitronectin and osteopontin are present (25,26).…”

“…Survey of recent reports emphasized their ability to promote contractile phenotype of the smooth muscle cells (34). Entactin is a glycoprotein also found in the lamina lucida of the basement membrane where it binds laminin and collagen type IV (26).…”

“…Collagen and reticular fibers are composed of protein collagen, while elastic fibers are primarily composed of elastin (1)(2)(3)(4). Collagen fibers play a major structural role and are the main supportive elements in the connective tissue.…”

“…Its basic role is structural support of blood vessel wall and to serve as a mechanical barrier for infective agents. The latter is achieved by the activity of immune cells and phagocytes (1)(2)(3)(4).…”