Prasugrel as Antiplatelet Therapy in Patients With Acute Coronary Syndromes or Undergoing Percutaneous Coronary Intervention

Fletcher, Barbara J.; Thalinger, Karen

doi:10.4037/ccn2010384

Critical Care Nurse

2010

DOI: 10.4037/ccn2010384

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Prasugrel as Antiplatelet Therapy in Patients With Acute Coronary Syndromes or Undergoing Percutaneous Coronary Intervention

Barbara J. Fletcher

Karen Thalinger²

Abstract: The authors provide information on prasugrel, compare and contrast it with clopidogrel, and review the use of prasugrel in patients who require an antiplatelet agent.

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Antiplatelet Therapy in Acute Coronary Syndromes

Berra

Fletcher²,

Handberg³

2011

Journal of Cardiovascular Nursing

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The care of cardiovascular patients experiencing a myocardial infarction (MI) has evolved from simple bed rest and relief of pain to complex interventions and multiple medications that target both the short- and long-term risks associated with atherosclerosis and ischemia. Even the terminology has changed, from MI to acute coronary syndromes (ACSs). The term, acute coronary syndrome, refers to the clinical symptoms resulting from acute myocardial ischemia; it encompasses unstable angina, non-ST-elevation MI, and ST-elevation MI. Antiplatelet therapies are critically important in the management of patients with ACS. Antiplatelet therapies interfere with platelet aggregation and platelet activation both acutely and chronically and thus impact the development of acute MI. Thus, they are prescribed for millions of patients with ACS. As a result of this progress in treatment, nursing management of persons with ACS has also evolved. This article reviews the pathophysiology of ACS, the role of antiplatelet therapies, their effects on platelet adhesion, and the role of the nurse in caring for patients with ACS who are prescribed these important therapies.

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Antiplatelet Therapy in Acute Coronary Syndromes

Berra

Fletcher²,

Handberg³

2011

Journal of Cardiovascular Nursing

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show abstract

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Prasugrel as Antiplatelet Therapy in Patients With Acute Coronary Syndromes or Undergoing Percutaneous Coronary Intervention

Abstract: The authors provide information on prasugrel, compare and contrast it with clopidogrel, and review the use of prasugrel in patients who require an antiplatelet agent.

Cited by 1 publication

References 53 publications

Antiplatelet Therapy in Acute Coronary Syndromes

Antiplatelet Therapy in Acute Coronary Syndromes

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