Practitioner Review: Treatment of Obsessive‐Compulsive Disorder in Children and Adolescents

In this report, which is an update of a guideline published in 2002 (Bandelow et al. 2002, recommendations for the pharmacological treatment of anxiety disorder, obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are presented. Since the publication of the first version of this guideline, a substantial number of new randomized controlled studies of anxiolytics have been published. In particular, more relapse prevention studies are now available that show sustained efficacy of anxiolytic drugs. The recommendations, developed by the World Federation of Societies of Biological Psychiatry (WFSBP) Task Force for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders, a consensus panel of 30 international experts, are now based on 510 published randomized, placebo-or comparator-controlled clinical studies (RCTs) and 130 open studies and case reports. First-line treatments for these disorders are selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs) and the calcium channel modulator pregabalin. Tricyclic antidepressants (TCAs) are equally effective for some disorders, but many are less well tolerated than the SSRIs/ SNRIs. In treatment-resistant cases, benzodiazepines may be used when the patient does not have a history of substance abuse disorders. Potential treatment options for patients unresponsive to standard treatments are described in this overview. Although these guidelines focus on medications, non-pharmacological were also considered. Cognitive behavioural therapy (CBT) and other variants of behaviour therapy have been sufficiently investigated in controlled studies in patients with anxiety disorders, OCD, and PTSD to support them being recommended either alone or in combination with the above medicines.

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“…Behavioural treatment strategies involving exposure and relapse prevention are considered most effective (Rapoport and Inoff-Germain 2000).…”

Section: Other Medicationsmentioning

confidence: 99%

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision

Bandelow

Zohar

Hollander

et al. 2008

The World Journal of Biological Psychiatry

711

410

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“…An advantage of this typology is that it helps connect pragmatic research on rituals with other disciplines such as clinical linguistics and psychology (e.g. Marks 1987;Rapoport 1989;Ciarocchi 1995), education studies (e.g. Sears and Sears 2005), and anthropology (e.g.…”

Section: Interactional Situatednessmentioning

confidence: 99%

Convention and Ritual (Im)politeness

Terkourafi

Kádár

2017

The Palgrave Handbook of Linguistic (Im)politeness

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“…CBT (specifically, exposure of the patient to the triggers of their obsessions and compulsions with response prevention) is well documented as a successful treatment of childhood-onset OCD (37). Both intensive (daily) and weekly CBT are effective treatments for childhood-onset OCD (38).…”

Section: Cbt the Optimum Treatment For Childhood-onset Ocd Is A Combi-mentioning

confidence: 99%

“…The main objectives of CBT are identifying the triggers of obsessions and compulsions and designing personalized exposure and response prevention (ERP) strategies that can be practiced outside the therapy sessions (37,40). In adults with OCD and partial response to treatment with a serotonin reuptake inhibitor, such as clomipramine or various selective serotonin reuptake inhibitors (SSRIs) (discussed below), the addition of ERP is an effective strategy for reducing OCD symptoms (41).…”

Section: Cbt the Optimum Treatment For Childhood-onset Ocd Is A Combi-mentioning

confidence: 99%

Children with obsessive-compulsive disorder: are they just “little adults”?

Kalra¹,

Swedo²

2009

J. Clin. Invest.

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Childhood-onset obsessive-compulsive disorder (OCD) affects 1%-2% of children and adolescents. It is characterized by recurrent obsessions and compulsions that create distress and interfere with daily life. The symptoms reported by children are similar to those seen among individuals who develop OCD in adulthood, and the two groups of patients are treated with similar symptom-relieving behavior therapies and medications. However, there are differences in sex ratios, patterns of comorbidity, and the results of neuroimaging studies that might be important. Here we review the diagnosis and treatment of childhood-onset OCD in light of pediatric and adult studies. We also discuss current knowledge of the pathophysiology of the disorder. Despite advances in this area, further research is needed to understand better the etiopathogenesis of the disorder and to develop new, more effective therapeutic options.

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Practitioner Review: Treatment of Obsessive‐Compulsive Disorder in Children and Adolescents

Cited by 66 publications

References 76 publications

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision

Convention and Ritual (Im)politeness

Children with obsessive-compulsive disorder: are they just “little adults”?

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