“…For example, adverse conditions in utero and during delivery may lead to changes in epigenetic profiles, gene expression, as well as neurotransmitters and proteins important for central nervous system development [van den Bergh et al, 2017;Wadhwa, Buss, Entringer, & Swanson, 2009]. Furthermore, early childhood exposures, such as childcare arrangements [Gomajee et al, 2018], (lack of) child stimulation [Gomajee et al, 2018;Rutter, 1998], (multiple) language exposure [Uljarevi c, Katsos, Hudry, & Gibson, 2016;Lehti et al, 2018], and screen use time [Christakis, Ramirez, Ferguson, Ravinder, & Ramirez, 2018;Wu et al, 2017] may also play a role in variations in early child development, but have been studied less frequently and are less clearly linked to clinical disorders. It must therefore be noted that delays in development related to such early childhood factors might not be permanent and indicative of a lifelong condition, such as ASD [Rutter, 1998] but rather transient and amenable to change.…”