Practice Variations in Anesthesia for Carotid Endarterectomies and Associated Outcomes

Gabriel, Rodney A.; Lemay, Allyson; Beutler, Sascha S.; Dutton, Richard P.; Urman, Richard D.

doi:10.1053/j.jvca.2015.06.014

Cited by 8 publications

(2 citation statements)

References 19 publications

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“…2 At present, carotid endarterectomy (CEA) has become a safe and effective method to treat severe and symptomatic moderate carotid artery stenosis. 3 However, carotid restenosis following CEA is one of the most important complications affecting the curative effect of surgery. Previous studies have shown that approximately 5-15% of patients with carotid artery stenosis experience restenosis following CEA.…”

Section: Introductionmentioning

confidence: 99%

<p>Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo</p>

Zhang

Yang

et al. 2020

DDDT

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Objective: The present study aimed to assess the effect of curcumin (Cur) on carotid artery restenosis following carotid endarterectomy (CEA) and its associated mechanism in vivo and in vitro. Methods: Ang II was used to induce excessive proliferation of rabbit aortic smooth muscle cells (CCC-SMC-1) in order to establish a hemadostenosis cell model. Similarly, the animal model of carotid artery restenosis was established by carotid artery gas drying injury combined with high-fat feed prior to CEA. CCC-SMC-1 cells and animals were treated by Cur and its effects on neointimal hyperplasia, inflammation and oxidative stress were detected and observed. The proteins that were associated with the Raf/MEK/ERK pathway were detected in cells and rabbit carotid artery tissues. Results: Cur inhibited the proliferation of smooth muscle cells and neointimal formation and reduced the inflammation and oxidative stress indices. Concomitantly, Cur reduced the phosphorylation of the Raf/MEK/ERK pathway proteins. Conclusion: Cur could inhibit carotid restenosis following CEA by inhibiting the activation of the Raf/MEK/ERK pathway.

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Section: Introductionmentioning

confidence: 99%

<p>Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo</p>

Zhang

Yang

et al. 2020

DDDT

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“…106,107 The share of RA in the overall structure of pain management during CEA ranges from 6 to 74%, in some clinics reaching 99% -such a wide range is largely explained by the preferences of clinics and their technical equipment. [108][109][110] The studies carried out still have not given a clear answer to the question -which of the above methods has undeniable advantages. [70][71][72][73][74]111 The main advantages of GA are immobility of the patient, decreased metabolism of brain cells and its protection during ischemia, adequate control of airway patency, external respiratory function and carbon dioxide concentration, reduced reaction to operational stress.…”

Section: Craniohypothermiamentioning

confidence: 99%

Analysis of the history of the search for methods of protecting the brain during operations on the internal carotid artery

Konyssov,

Batrashov,

Sukhareva

et al. 2023

BSK

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The review covers the first studies of the vessels of the brain. The history of the emergence and development of the doctrine of protecting the brain during operations on the carotid arteries is given. Experience has been accumulated in the development of the doctrine of surgical protection of the brain during primary operations on the carotid arteries and compression of the carotid arteries. The analysis of existing and existing methods was carried out. Based on the above analysis, ways of further development of methods of protecting the brain during operations on the carotid arteries are shown.

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Awake Sedation With Propofol Attenuates Intraoperative Stress of Carotid Endarterectomy in Regional Anesthesia

Szabó

Mayer

Horváth‐Szalai

et al. 2020

Annals of Vascular Surgery

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Practice Variations in Anesthesia for Carotid Endarterectomies and Associated Outcomes

Cited by 8 publications

References 19 publications

<p>Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo</p>

<p>Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo</p>

Analysis of the history of the search for methods of protecting the brain during operations on the internal carotid artery

Awake Sedation With Propofol Attenuates Intraoperative Stress of Carotid Endarterectomy in Regional Anesthesia

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