Practice Parameter for the Assessment and Treatment of Children and Adolescents With Tic Disorders

Murphy, Tanya K.; Lewin, Adam B.; Storch, Eric A.; Stock, Saundra

doi:10.1016/j.jaac.2013.09.015

Cited by 213 publications

(177 citation statements)

References 132 publications

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“…In both studies, adverse events were tracked, and none were associated with CBIT. Based largely on these two large studies, CBIT has been recommended as a firstline treatment for those with GTS in multiple practice guidelines [153][154][155] .…”

Section: Thoughts For Dougmentioning

confidence: 99%

Gilles de la Tourette syndrome

Robertson

Eapen

Singer

et al. 2017

Nat Rev Dis Primers

277

241

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The unstructured abstract of 200 words maximum should summarize the main points of the article. All information mentioned in the abstract must be addressed somewhere in the main article. The abstract should not contain references or display item citations. Gilles de la Tourette Syndrome (GTS), a reasonably common disorder, has had a long, tortuous and somewhat controversial history. First and well described in the 18th century 1,2 , the main features of GTS have, however, remained fairly constant. The core diagnostic features are multiple motor and one or more vocal (phonic) tics lasting for over a year. In addition, almost pathognomic, but not necessary, features described in the early documentations include coprolalia (involuntary, inappropriate swearing), and echophenomena (copying behaviours), as well as many co-morbidities and psychopathologies 3 . Introduction [suggested 500 words, is 544 words -8 refs] Mary Robertson Thoughts for Mary -Your word count when combining sections 1 and 2 is 1001 (1000 limit)-so OKGTS was originally described in France and the majority of early literature came from and standardised schedules such as diagnostic confidence, measurement of severity, QoL, and assessment of both co-morbidities and co-existent psychopathologies are currently available.Large international collaborative consortia are engaged in studies exploring aetiological factors in particular, and some international treatment studies are also underway. Perhaps as a result of earlier small patient numbers, the treatment trials have given good clues to management, but unsurprisingly systematic reviews and meta-analyses have been hampered, giving disappointing, if not unexpected, results. Intriguingly medications from the typical NRDP -Gilles de la Tourette Syndrome 3 antipsychotic family including haloperidol, which first had documented success in 1961 6,7 are still being used, although successive generations of "atypicals" are currently more in vogue,as are medications such as alpha-2-adrenergic agonists. Interestingly, haloperidol remains the only medication prescribed on licence in many parts of the world. In contrast to disorders such as ADHD, in which it is clear which treatments work and which do not require further study 8 , a variety of treatment studies in GTS are still being undertaken, including using other medications (trying to improve efficacy and reduce side effects), behavioural therapies, deep brain stimulation (for refractory cases), and other more "alternative" methods such as "orthotics" (teeth braces). The GTS community has to first agree on how common GTS is and then seek funding for research in the areas of major importance.2. Epidemiology [suggested 500 words, is 444 words, 6 additional refs] Mary Robertson GTS was for many years thought to be not only very rare, but a bizarre curiosity, with sporadic case reports peppering the literature. The belief that GTS was uncommon at the very least was held by many until Comings 9 controversially suggested that GTS occurred in between 0.66% and...

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Section: Thoughts For Dougmentioning

confidence: 99%

Gilles de la Tourette syndrome

Robertson

Eapen

Singer

et al. 2017

Nat Rev Dis Primers

277

241

View full text Add to dashboard Cite

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“…In adolescents, urine drug screen for cocaine and stimulants may be needed. In cases of family history of hepatic disorders, measurement of serum copper and ceruloplasmin levels may be required to exclude Wilson's disease [33,34].…”

Section: Evaluation Of Cases With Tsmentioning

confidence: 99%

“…Evaluation of TS cases for comorbidities as OCD, ADHD, and learning disabilities is crucial as missed diagnosis of comorbidities could remarkably worsen the prognosis because they usually result in significant social, functional, and or academic impairment [3,34].…”

Section: Evaluation Of Cases With Tsmentioning

confidence: 99%

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Tourette Syndrome; Is It an Annoying Disorder or an Inspiring Companion??!!!

Zaky¹

2017

J Child Adolesc Behav

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Tourette syndrome (TS) is a hereditary neurobehavioral disorder which starts early during childhood and manifests with a group of motor and one or more vocal tics for a duration of a year at least. It tends to be a lifelong chronic disorder with many remissions and exacerbations but in general, it is not a degenerative disease and has no negative percussions on intelligence or life span. Cases with TS need proper professional evaluation to exclude any differential diagnoses and detect any comorbidities. Cognitive Behavior Therapy (CBT), medications, and supportive intervention are indicated for cases with significant functional impairment. Some sufferers consider TS a very annoying lifelong disorder while others think about it as an inspiring companion that makes them gifted, unique and special.

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“…Although substantial evidence exists for pharmacological and behavioral interventions for tics [73], there is a paucity of research evaluating the effectiveness of augmenting (or modifying) interventions to address social deficits within this population. Youth with tics may benefit from social skills training to improve peer relationships and/or effectively respond to teasing or rejection [74].…”

Section: Evidence-based Interventions For Improving Social Functioninmentioning

confidence: 99%

Social Deficits and Autism Spectrum Disorders in Tourette’s Syndrome

Hanks

Lewin

Mutch

et al. 2015

Curr Dev Disord Rep

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Chronic tic disorders, including Tourette's syndrome (TS), are neuropsychiatric disorders characterized by the childhood onset of motor and/or vocal tics. Youth with TS often experience disturbances in social functioning, which can negatively impact functioning and overall quality of life. We summarize the existing knowledge about social deficits in youth with TS, while highlighting the various ways that these deficits present in comorbid developmental disorders (i.e., autism spectrum disorders) as well as in other TS-related phenomenology impacting social functioning (i.e., comorbid psychiatric conditions, tic severity, and peer victimization). Further, we discuss how interventions for TS should aim to address not only tic severity, but also the multifaceted reasons for social deficits within this population. We conclude with a discussion of clinical implications and future directions for clinical intervention and research.

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Practice Parameter for the Assessment and Treatment of Children and Adolescents With Tic Disorders

Cited by 213 publications

References 132 publications

Gilles de la Tourette syndrome

Gilles de la Tourette syndrome

Tourette Syndrome; Is It an Annoying Disorder or an Inspiring Companion??!!!

Social Deficits and Autism Spectrum Disorders in Tourette’s Syndrome

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