“…Useless high F I O 2 can lead to hyperoxia, which has been associated with poor outcome in the ICU 23,24 and reported to worsen lung function during acute lung injury. 25 Hence, the necessity to maintain HFNC or HFFM was re-evaluated every 6 hours and if SpO 2 >96% was achieved sustainably with a Venturi mask 50%, the patient could be discharged from the ICU.…”