Practical Synthesis of (Z)‐Polyaromatic and Heteroaromatic Vinylacetylenes.

Abstract

Alkenes Q 0083Practical Synthesis of (Z)-Polyaromatic and Heteroaromatic Vinylacetylenes. -Two alternative and general pathways are developed. The synthetic utility of these methods is illustrated by transformation of electron-rich and electron-deficient heteroaromatic as well as aromatic carboxaldehydes to their (Z)-vinylacetylenes in good to excellent yields. -(HAYFORD*, A.; KALOKO, J. J.; EL-KAZAZ, S.; BASS, G.; HARRISON, C.; CORPREW, T.; Org. Lett. 7 (2005) 13, 2671-2673; Dep. Chem., East Carolina Univ., Greenville, NC 27858, USA; Eng.) -Y. Steudel 44-085