Practical one‐pot, two‐step protocol for the ultrasound‐assisted synthesis of new mono‐ and bis‐pyrrolidine‐2,5‐diones containing sulfonamide moiety

Abstract

A simple and efficient preparation of novel series of mono-and bis-pyrrolidine-2,5-diones containing sulfonamide moiety was described. The strategy involved sequential one-pot sulfonylation-nucleophilic substitution procedure and was found effective under ultrasound activation and used for the first time. This approach allows the synthesis of products in good to excellent yields in short reaction time.