Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome

Cantatore-Francis, Julie L.; Orlow, Seth J.

doi:10.1001/archdermatol.2009.220

Cited by 47 publications

(59 citation statements)

References 32 publications

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“…1 Cantatore-Francis and Orlow proposed that LAHS should be diagnosed only when there are more than 50% loose anagen hairs in the trichogram. 10 Trichoscopy (hair and scalp dermoscopy) is a rapid in-office technique, which has become a standard procedure in differential diagnosis of hair loss. 11,13 However, there are no specific trichoscopy features that favor the diagnosis of LAHS.…”

Section: Introductionmentioning

confidence: 99%

Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots

Rakowska¹,

Zadurska²,

Czuwara³

et al. 2015

J Dermatol Case Rep

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Background: Loose anagen hair syndrome (LAHS) is typically diagnosed in girls older than 2 years who present with hair that "will not grow". Hair microscopic examination shows absent inner and outer root sheaths, ruffling of the cuticle on the proximal hair shaft and deformed pigmented anagen bulbs.Objective: The aim of the study was to assess whether there are characteristic trichoscopic features favoring the diagnosis of LAHS. Patients and methods:Eighty nine children patients were included into the study (24 girls with LAHS, 25 with alopecia areata, 20 with telogen effluvium and 20 healthy children). In all groups trichoscopy was performed. Trichoscopy images were analyzed for abnormalities in the hairs shafts, the hair follicle openings and the interfollicular area.Results: Dirty dots were present in all groups. A unique feature of LAHS was the presence of rectangular black granular structures which differs from dense black dots seen in patients with alopecia areata. This feature was observed in 71% of patients with LAHS. Follicular units with single hairs constituted 92,9% of hair units in these patients (65,5% in telogen effluvium and 53% in the control group). Solitary yellow dots were found in 50% of patient with LAHS and in 24% of patients with alopecia areata, but was not found in control group or in patients with telogen effluvium. Conclusion:The trichoscopy features favoring the diagnosis of LAHS are: rectangular black granular structures, solitary yellow dots and major predominance of follicular units with single hairs. (J Dermatol Case Rep. 2015; 9(1): 1-5)

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Section: Introductionmentioning

confidence: 99%

Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots

Rakowska¹,

Zadurska²,

Czuwara³

et al. 2015

J Dermatol Case Rep

View full text Add to dashboard Cite

show abstract

“…LAS is most common in girls (36 : 1 female to male ratio) and usually presents in children less than 6 years of age [200] . Most patients have blonde or light brown hair.…”

Section: Loose a Nagen S Yndromementioning

confidence: 99%

“…It is now clear that normal prepubescent children may have a few loose anagen hairs found on a gentle hair pull and that the criteria for diagnosis of LAS must include either a designated number of loose anagen hairs (at least 3 or perhaps at least 10, per hair pull [5,202] ) or a percentage of all hairs obtained on hair pull (50% has been suggested) [200] . Other hair shaft abnormalites may be seen in LAS other than loose anagen hairs, including trichorhexis nodosa and tiger -tail polarization [200] .…”

Section: Loose a Nagen S Yndromementioning

confidence: 99%

“…Other hair shaft abnormalites may be seen in LAS other than loose anagen hairs, including trichorhexis nodosa and tiger -tail polarization [200] . …”

Section: Loose a Nagen S Yndromementioning

confidence: 99%

“…LAS has been reported with a variety of syndromes [200] but it is unclear of the defi nition of LAS utilized in these reports, or whether there may have been artifactual creation of loose anagen hairs by too much traction on a hair pull in very young children. Two siblings with ocular colobomas, anagen hair shedding and decreased hair growth rate have been described [203] .…”

Section: Chapter 148mentioning

confidence: 99%

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Acquired Disorders of Hair

Harries,

Holmes,

McMichael

et al. 2024

Rook's Textbook of Dermatology

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This chapter reviews acquired hair disorders, including common scarring and non‐scarring alopecia presentations, conditions characterised by excessive body hair growth and acquired hair shaft disorders. We also describe the biology of normal hair follicles, including structure, hair cycle control and immunity, to better understand the mechanisms underlying these conditions. We present methods for clinical assessment, recommended investigation and management of each disease, and present summaries of frequently used therapeutics and cosmetic options employed when treating these problems.

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Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome

Abstract: To better categorize the epidemiologic profile, clinical features, and disease associations of loose anagen hair syndrome (LAHS) compared with other forms of childhood alopecia.

Cited by 47 publications

References 32 publications

Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots

Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots

Hair Disorders

Acquired Disorders of Hair

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