Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs

Broyles, Ana Dioun; Banerji, Aleena; Barmettler, Sara; Biggs, Catherine M.; Blumenthal, Kimberly G.; Brennan, Patrick J.; Breslow, Rebecca G.; Brockow, Knut; Buchheit, Kathleen M.; Cahill, Katherine N.; Cernadas, Josefina; Chiriac, Anca Mirela; Crestani, Elena; Demoly, Pascal; Dewachter, Pascale; Dilley, Meredith A.; Farmer, Jocelyn R.; Foer, Dinah; Fried, Ari J.; Garon, Sarah L.; Giannetti, Matthew P.; Hepner, David L.; Hong, Deli; Hsu, Joyce T.; Kothari, Parul H.; Kyin, Timothy; Lax, Timothy; Lee, Min Jung; Lee-Sarwar, Kathleen; Liu, Anne; Logsdon, Stephanie; Louisias, Margee; MacGinnitie, Andrew J.; Maciag, Michelle C.; Minnicozzi, Samantha; Norton, Allison E.; Otani, Iris M.; Park, Miguel; Patil, Sarita U.; Phillips, Elizabeth; Picard, Matthieu; Platt, Craig D.; Rachid, Rima; Rodríguez, T. Palomeque; Romano, Antonino; Stone, Cosby A.; Torres, Marı́a José; Verdú, Miriam; Wang, Alberta L.; Wickner, Paige G.; Wolfson, Anna R.; Wong, Johnson T.; Yee, Christina S.K.; Zhou, Jin-Jian; Castells, Mariana

doi:10.1016/j.jaip.2020.08.006

Cited by 116 publications

(99 citation statements)

References 835 publications

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“…These results reconcile clinical and experimental data on the role of IgE and IgG during anaphylaxis and can modify our biological diagnostic approaches to NMBAinduced anaphylaxis, even if skin tests remain major tools for IgE-mediated reactions. Indeed, we can now suggest to implement the classical biological evaluation of suspected NMBA anaphylaxis 74,75 by exploring both IgE-basophil and IgGneutrophil pathways.…”

Section: Nmba-induced Anaphylaxis Exemplflies Multiple Mechanisms At Playmentioning

confidence: 99%

Mechanisms of human drug-induced anaphylaxis

Bruhns

Chollet‐Martin

2021

Journal of Allergy and Clinical Immunology

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Section: Nmba-induced Anaphylaxis Exemplflies Multiple Mechanisms At Playmentioning

confidence: 99%

Mechanisms of human drug-induced anaphylaxis

Bruhns

Chollet‐Martin

2021

Journal of Allergy and Clinical Immunology

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“…Las reacciones usualmente son de tipo no inmediatas. 49 En este escenario se han utilizado con éxito protocolos de desensibilización, tanto rápida como lenta; en el Cuadro 4 se muestra un ejemplo de desensibilización rápida a betalactámico, para una dosis meta de 1 g. 50…”

Section: Dosisunclassified

“…Intervalo entre cada dosis de 15 minutos47 Cuadro 4. Ejemplo de protocolo de desensibilización intravenosa para 1 g de antibiótico antilactámico50…”

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Hipersensibilidad a antibióticos betalactámicos: algoritmos de manejo y desensibilización como alternativa terapéutica vital

Cardona

Santamaría

Guevara-Saldaña

et al. 2021

RAM

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Las reacciones de hipersensibilidad pueden ser complejas y poner en peligro la vida de los pacientes, más cuando se involucran medicamentos como los antibióticos betalactámicos. A la fecha, se dispone de algoritmos diagnósticos y aplicaciones móviles que facilitan el abordaje clínico, así como pruebas de laboratorio y procedimientos más especializados, como las pruebas cutáneas y de exposición controlada, útiles para la identificación de la sustancia implicada y para la selección de alternativas terapéuticas seguras y efectivas. Desde hace varios años, el procedimiento de desensibilización se ha posicionado como una herramienta vital para el alergólogo clínico y los pacientes, y es clave para mejorar los desenlaces clínicos, tanto la supervivencia como la calidad de vida.

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“…Notwithstanding, allergies to these insulins have been described. Short acting insulin preparations are least immunogenic because rapid absorption is thought to decrease immune exposure 3 .…”

Section: Introductionmentioning

confidence: 99%

Rapid Desensitization for Insulin Allergy in Type 1 Diabetes Using an Insulin Pump: A Case Report and Literature Review

Tian

Lee

Lim

et al. 2021

AACE Clinical Case Reports

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs

Cited by 116 publications

References 835 publications

Mechanisms of human drug-induced anaphylaxis

Mechanisms of human drug-induced anaphylaxis

Hipersensibilidad a antibióticos betalactámicos: algoritmos de manejo y desensibilización como alternativa terapéutica vital

Rapid Desensitization for Insulin Allergy in Type 1 Diabetes Using an Insulin Pump: A Case Report and Literature Review

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