Practical Experience with Sonographically Guided Phenol Instillation of Stump Neuroma: Predictors of Effects, Success, and Outcome

Gruber, Hannes; Glodny, Bernhard; Bodner, Gerd; Kopf, H; Bendix, Nadine; Galiano, Klaus; Strasak, Alexander; Peer, Siegfried

doi:10.2214/ajr.07.2050

Cited by 64 publications

(49 citation statements)

References 30 publications

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“…Additionally, spontaneous and aberrant signaling from the injured sensory nerve results in neuropathic pain symptoms, commonly observed in postamputation residual limb pain [12,13].…”

Section: Not Possible With Cryoneurolysismentioning

confidence: 99%

Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves

Ilfeld

Preciado

Trescot

2016

Expert Review of Medical Devices

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Introduction: Cryoneurolysis is the direct application of low temperatures to reversibly ablate peripheral nerves to provide pain relief. Recent development of a handheld cryoneurolysis device with small gauge probes and an integrated skin warmer broadens the clinical applications to include treatment of superficial nerves, further enabling treatments for pre-operative pain, post-surgical pain, chronic pain, and muscle movement disorders. Areas covered: Cryoneurolysis is the direct application of cold temperatures to a peripheral nerve, resulting in reversible ablation due to Wallerian degeneration and nerve regeneration. Use over the last 50 years attests to a very low incidence of complications and adverse effects. Cryoprobes have traditionally been applied through a surgical incision; but, recent technical advances allow percutaneous administration. A new hand-held device is now approved for use within the United States. Cryoneurolysis has been used to treat postoperative and chronic pain states as well as spasticity. Expert commentary: Changes in the US healthcare system such as a push for the reduction of opioid use and the incorporation of Diagnostic Related Group codes, as well as recent technological advances including a handheld unit that allows for treatment of superficial nerves while protecting the skin from damage, may contribute to the resurgence of cryoneurolysis for the treatment of peripheral nerves. ARTICLE HISTORY

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“…Additionally, spontaneous and aberrant signaling from the injured sensory nerve results in neuropathic pain symptoms, commonly observed in postamputation residual limb pain [12,13].…”

Section: Not Possible With Cryoneurolysismentioning

confidence: 99%

Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves

Ilfeld

Preciado

Trescot

2016

Expert Review of Medical Devices

View full text Add to dashboard Cite

show abstract

“…Due to the lack of the nerve scaffolding, axons will regenerate aberrantly at the injury site and will not be able to continue to the distal nerve stump [22]. Additionally, spontaneous and aberrant signaling from the injured sensory nerve result in neuropathic pain symptoms, commonly observed in amputation stump pain [23,24]. Some surgical methods used to repair nerve transection include suturing to join the proximal and distal stump, auto-or allo-grafting of nerve gaps, or use of biological or biosynthetic conduits [25].…”

Section: IImentioning

confidence: 99%

Significance of Clinical Treatments on Peripheral Nerve and its Effect on Nerve Regeneration

Hsu¹

2014

J Neurol Disord

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Some neurological disorders that cannot be managed with medication can alternatively be directly treated either at the sensory and/or motor nerve(s). In particular, chronic pain and/or muscle spasticity are a couple types of symptoms that can potentially be treated at the associated nerve. Various chemicals and medical devices are currently being employed in the clinic to treat peripheral nerves. Treatment of sensory nerves is typically used to attenuate chronic pain symptoms, while motor nerves are targeted for spasticity symptoms. A majority of treatment methods currently used in the field involve nerve injury and denervation of the target tissue through different mechanisms of action. Depending on the type and severity of the treatment, the nerve may or may not fully regenerate to a normal state. This article will review the various types of clinical methods used to treat neurological disorders and discuss the possible outcomes of nerve regeneration.

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“…6). Nach Injektion und während der Retraktion wird die Nadel mit Natriumchlorid gespült, um eine Verteilung des Phenols im umliegenden Gewebe zu verhindern [47]. Dieses standardisierte Procedere kann in mehrfachen Sitzungen wiederholt werden, um die Erfolgsrate zu erhöhen.…”

Section: Untersuchungsalgorithmusunclassified

Ultraschallgesteuerte Interventionen am peripheren Nervensystem

Loizides

Grüber

Peer³

et al. 2017

Radiologe

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Practical Experience with Sonographically Guided Phenol Instillation of Stump Neuroma: Predictors of Effects, Success, and Outcome

Abstract: The high-resolution sonographically guided neurosclerosis procedure had a significantly better outcome than other documented treatments. Sonographically guided neurosclerosis should be included in the management of chronic phantom limb and stump pain.

Cited by 64 publications

References 30 publications

Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves

Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves

Significance of Clinical Treatments on Peripheral Nerve and its Effect on Nerve Regeneration

Ultraschallgesteuerte Interventionen am peripheren Nervensystem

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