Practical aspects of simultaneous determination of selenium and ytterbium by neutron activation analysis

Czauderna, M.; Samochocka, K.; Kalicki, A.

doi:10.1007/bf02519668

Cited by 5 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Because the reaction products of SeOz with 2-MP and 6-MP and 2-MP and 6-MP all give peaks in the 250-350 nm range a modified method of continuous variations was used. 14…”

Section: Methodsmentioning

confidence: 99%

Selenotrisulphides from mercaptopurines

Czauderna¹,

Samochocka²

1983

J. Chem. Soc., Perkin Trans. 2

View full text Add to dashboard Cite

“…Because the reaction products of SeOz with 2-MP and 6-MP and 2-MP and 6-MP all give peaks in the 250-350 nm range a modified method of continuous variations was used. 14…”

Section: Methodsmentioning

confidence: 99%

Selenotrisulphides from mercaptopurines

Czauderna¹,

Samochocka²

1983

J. Chem. Soc., Perkin Trans. 2

View full text Add to dashboard Cite

“…Селенит и селенат натрия. Неорганические соединения -селенат, селенит натрия вступают в неферментативную реакцию с восстановленным глутатионом (GSH) с образованием селенодиглутатиона (GS-Se-SG) [ Наши исследования показали, что интермедиат селенодиглутатион присутствует в реакционной смеси в незначительных количествах [34], нестабилен [35] и не может служить полноценным обменным пулом (буфером) для организма.…”

Section: серы металлический селен -самая термодинамически устойчиваяunclassified

Metabolism and Mechanism of Toxicity of Selenium-Containing Supplements Used for Optimizing Human Selenium Status

Poluboyarinov

Elistratov²,

Shvets

2019

Fine Chem. Tech.

View full text Add to dashboard Cite

The work presents a review devoted to the metabolism and the mechanism of toxicity of seleniumcontaining supplements: elemental selenium, sodium selenite, diacetophenonyl selenide, selenopyrane, ebselen, dimethyl dipyrasolyl selenide and selenium-containing amino acids used for correction of selenium deficiency. Elemental selenium penetrating through cell walls, but not through transport channels demonstrates poorly predicted and difficultly regulated bioavailability. Sodium selenate is known to be the most toxic form of selenium in food. The metabolism of xenobiotic diacetophenonyl selenide resembles that of sodium selenide. The xenobiotic reacts with thiols, for instance, with the reduced form of glutathione leading to the formation of hydrogen selenide. Ebselen is not considered to be a well bioavailable form of selenium and thus possesses low toxicity. Xenobiotic selenopyrane eliminates selenium only in processes of xenobiotic liver exchange, and in our investigations - partially in acid-catalyzed hydrolysis. The metabolism of xenobiotic dimethyl dipyrasolyl selenide having low toxicity is poorly investigated. The toxicity of high doses of selenomethionine is determined by the possibility of incorporation in proteins and vitally important enzymes with dramatic changes of protein quaternary structure. The toxicity of high doses of methylselenocysteine seems to be caused by the lack of an exchange pool in the body and quick regeneration of hydrogen selenide from methylselenol which is formed as a result of enzymatic destruction of this amino acid. Also the issue of the most prospect selenium donor is discussed. The physiological compatibility, the low toxicity, the presence of an exchangeable pool in the organism, the antioxidantal properties and the simplicity of production indicate selenocystine as an optimal selenium donor.

show abstract

Analysis by nuclear reactions and activation

Bujdosó

1985

Journal of Radioanalytical and Nuclear Chemistry, Articles

View full text Add to dashboard Cite

Practical aspects of simultaneous determination of selenium and ytterbium by neutron activation analysis

Cited by 5 publications

References 4 publications

Selenotrisulphides from mercaptopurines

Selenotrisulphides from mercaptopurines

Metabolism and Mechanism of Toxicity of Selenium-Containing Supplements Used for Optimizing Human Selenium Status

Analysis by nuclear reactions and activation

Contact Info

Product

Resources

About