2019
DOI: 10.1097/md.0000000000015010
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Practical application of the ATOM study

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Cited by 2 publications
(2 citation statements)
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“…Changing to the HEARTS ACE-I or ARB + diuretic protocol in which all patients are on at least two medications increases the cost of treating patients, but combination therapy has been demonstrated to significantly increase rates of hypertension control with few adverse side effects compared to monotherapy (26)(27)(28)(29)(30). Future analyses examining the cost-effectiveness of treatment regimens could lend insight into how much health benefit is purchased for the additional cost (21), providing decision makers with information that could be used to inform national pharmacological treatment guidelines.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Changing to the HEARTS ACE-I or ARB + diuretic protocol in which all patients are on at least two medications increases the cost of treating patients, but combination therapy has been demonstrated to significantly increase rates of hypertension control with few adverse side effects compared to monotherapy (26)(27)(28)(29)(30). Future analyses examining the cost-effectiveness of treatment regimens could lend insight into how much health benefit is purchased for the additional cost (21), providing decision makers with information that could be used to inform national pharmacological treatment guidelines.…”
Section: Discussionmentioning
confidence: 99%
“…The scenario applies the same per unit medication costs reported within the survey instrument, but if a different medication strength was specified in the protocols than had been reported in the survey instrument (e.g., amlodipine 10 mg instead of 5 mg), medication cost is increased by 50% following published assumptions (20). To determine the percent of patients with a given risk factor who receive low-medium-and high-intensity treatment regimens, we drew on risk-factorseverity distribution data (e.g., for those with hypertension, the percent with systolic blood pressure levels 140 to <150 mmHg, 150 to <160 mmHg, or >160 mmHg) from Mexico's 2018 National Health and Nutrition Survey (ENSANUT) and mapped it against pharmacological regimen intensity recommendations from published literature or protocols (19,21,22).…”
Section: Costing Framework By Hearts Componentmentioning
confidence: 99%