PPO/PEO modified hollow fiber membranes improved sensitivity of 3D cultured hepatocytes to drug toxicity via suppressing drug adsorption on membranes

Shen, Chong; He, Wei; Wang, Qichen; Zhang, Guoliang

doi:10.1016/j.colsurfb.2014.10.023

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…Micro-pollutants, which are usually hydrophobic and charged organic molecules having a molecular weight of less than 1000 Da, can easily be absorbed onto the highly hydrophobic and charged synthetic polymer surface [ 60 ].…”

Section: Resultsmentioning

confidence: 99%

Removal of Organics with Ion-Exchange Resins (IEX) from Reverse Osmosis Concentrate

et al. 2023

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Reverse osmosis concentrate (ROC) produced as the by-product of the reverse osmosis process consists of a high load of organics (macro and micro) that potentially cause eco-toxicological effects in the environment. Previous studies focused on the removal of such compounds using oxidation, adsorption, and membrane-based treatments. However, these methods were not always efficient and formed toxic by-products. The impact of ion-exchange resin (IEX) (Purolite®A502PS) was studied in a micro-filtration–IEX hybrid system to remove organics from ROC for varying doses of Purolite® A502PS (5–20 g/L) at a flux of 36 L/m2h. The purolite particles in the membrane reactor reduced membrane fouling, evidenced by the reduction of transmembrane pressure (TMP), by pre-adsorbing the organics, and by mechanically scouring the membrane. The dissolved organic carbon was reduced by 45–60%, out of which 48–81% of the hydrophilics were removed followed by the hydrophobics and low molecular weight compounds (LMWs). This was based on fluorescence excitation-emission matrix and liquid chromatography-organic carbon detection. Negatively charged and hydrophobic organic compounds were preferentially removed by resin. Long-term experiments with different daily replacements of resin are suggested to minimize the resin requirements and energy consumption.

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Section: Resultsmentioning

confidence: 99%

Removal of Organics with Ion-Exchange Resins (IEX) from Reverse Osmosis Concentrate

et al. 2023

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“…As shown in Table 1, the water flux of PSU and PSU-g-SBMA HFM were similar (about 250 LMH). However, the PSU-g-SBMA HFM displayed much lower static adsorption of BSA and fibrin than PSU HFM and other PSU membranes (Shen et al 2014), indicating its anti-fouling property. The flux recovery rate (FRR) and BSA rejection rate of the two HFM were also listed in Table 1.…”

Section: Resultsmentioning

confidence: 81%

PSU-g-SBMA hollow fiber membrane for treatment of oily wastewater

Shen

Zhang

Meng

2021

Water Science and Technology

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Ultrafiltration membranes can intercept oil particles smaller than 10 μm, but the membranes are easy to be contaminated by oil due to their hydrophobicity. To treat various oily wastewater, we prepared a hydrophilic hollow fiber membrane (HFM) with anti-fouling property by grafting sulfobetaine methacrylate (SBMA) onto polysulfone (PSU). For six simulated wastewater containing emulsified oil at 1,000 mg/L, the PSU-g-SBMA HFM was able to remove 98.5–99.7% of oil, higher than that of PSU HFM at 91.1–98.9%. The oil concentration in filtrate was less than 15 mg/L, which could meet the discharge standard of wastewater. The water flux of PSU-g-SBMA HFM can be completely recovered after being washed by rhamnolipid and alkali solution, while the same cleaning process could not recover the PSU HFM. As found, the contact angles of oil droplets on the PSU-g-SBMA membrane were larger than those on PSU membrane, which indicated the improved hydrophilicity by PSU-g-SBMA. For 48 h of filtration to soybean and diesel oil/water emulsion, the effect of PSU-g-SBMA HFM was stable and the flux could be completely recovered by cleaning. Therefore, we provided a new method for oily wastewater treatment, which can efficiently and energy-saving remove various oil substances in wastewater.

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In vitro Models for Chemical Toxicity: Review of their Applications and Prospects

Rim

2019

Toxicol. Environ. Health Sci.

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PPO/PEO modified hollow fiber membranes improved sensitivity of 3D cultured hepatocytes to drug toxicity via suppressing drug adsorption on membranes

Cited by 5 publications

References 27 publications

Removal of Organics with Ion-Exchange Resins (IEX) from Reverse Osmosis Concentrate

Removal of Organics with Ion-Exchange Resins (IEX) from Reverse Osmosis Concentrate

PSU-g-SBMA hollow fiber membrane for treatment of oily wastewater

In vitro Models for Chemical Toxicity: Review of their Applications and Prospects

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