Pp011-Sun Functional and Nutritional Assessment of Chronically Critically Ill Patients Undergoing Weaning: A Prospective Cohort Study

Papirov, G.; Volvovitz, K.; Zeidenberg, L.; Fisher, Douglas; Grozovski, E; Kagan, Ilya; Singer, P.

doi:10.1016/s1744-1161(11)70065-5

Cited by 2 publications

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“…Brandi et al 58 suggested that indications for measuring energy expenditure in ICU ventilated patients should include those who fail to respond to the estimated nutrition needs, have single‐organ or multiorgan failure, need prolonged ICU care and artificial nutrition, or have side effects of artificial nutrition and are in the process of weaning from mechanical ventilation. In a study of 176 chronically ventilated patients admitted to a geriatric rehabilitation center for weaning from mechanical ventilation, Papirov et al 59 found that the Harris‐Benedict equation predicted 1385 ± 265 kcal/d, the measured REE was 1473 ± 420 kcal/d, and the actual amount of enteral feeding administered was excessive, reaching 1649 ± 257 kcal/d. Length of ventilation is increased in patients with significant overnutrition or undernutrition, 30 , 60 and length of ventilation could be reduced by reduction of the calorie intake in stable patients with elevated VCO 2 58 , 61 …”

Section: Practice Applications Of Indirect Calorimetrymentioning

confidence: 99%

Clinical Guide for the Use of Metabolic Carts

Singer

2015

Nut in Clin Prac

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Critically ill patients often require nutrition support, but accurately determining energy needs in these patients is difficult. Energy expenditure is affected by patient characteristics such as weight, height, age, and sex but is also influenced by factors such as body temperature, nutrition support, sepsis, sedation, and therapies. Using predictive equations to estimate energy needs is known to be inaccurate. Therefore, indirect calorimetry measurement is considered the gold standard to evaluate energy needs in clinical practice. This review defines the indications, limitations, and pitfalls of this technique and gives practice suggestions in various clinical situations.

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Section: Practice Applications Of Indirect Calorimetrymentioning

confidence: 99%

Clinical Guide for the Use of Metabolic Carts

Singer

2015

Nut in Clin Prac

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From Mitochondrial Disturbances to Energy Requirements

Singer¹

2012

World Review of Nutrition and Dietetics

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An organism requires nutrients to produce ATP, but the substrate oxidative process increases oxidative stress. This fine-tuning is centralized in the mitochondria, which is able to react to any excess or deprivation in nutrients. In normal subjects, these regulations can induce inflammatory effect and obesity in energy excess and a decrease in oxidative stress in a hypocaloric diet. In the critically ill patient, the mitochondrial capacity to cope with severe illness not only includes oxygen supply and nutrient and substrate supply with adequate coupling efficiency of oxidative phosphorylation, but also limitation of hormonal disturbances, maintenance of mitochondrial gene transcription, and limitation of the activity of mitochondrial proteases that lead to autophagy. In the macroscopic perspective, overfeeding increases glycemia, infection rate, length of ventilation, and length of stay. Many observational studies correlate hypocaloric regimens with increased complications and mortality. This chapter integrates the mitochondrial mechanism's modeling nutrient administration with acute illness.

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Pp011-Sun Functional and Nutritional Assessment of Chronically Critically Ill Patients Undergoing Weaning: A Prospective Cohort Study

Cited by 2 publications

References 0 publications

Clinical Guide for the Use of Metabolic Carts

Clinical Guide for the Use of Metabolic Carts

From Mitochondrial Disturbances to Energy Requirements

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