PP.16.06

Abstract

ance, Group A patients had higher total cholesterol (224 ± 46 vs 211 ± 40 mg/dL, p < 0.001), non-HDL cholesterol (177 ± 42 vs 150 ± 52 mg/dL, p = 0.001), and uric acid levels (5.4 ± 1.4 vs 5.2 ± 1.3, p = 0.023) than Group B patients. VAI was directly correlated with total and non-HDL cholesterol in the whole sample and in either sex; a direct correlation with blood glucose was also present in women and in the whole sample, but not in men. Conversely, VAI was inversely correlated with age, both in men (r = −0.220, p = 0.02) and in the whole sample (r = −0.120, p < 0.01). Ten-year coronary risk (CR) was assessed by the Framingham equation in patients aged less than 74 years and without history of overt cardiovascular disease (N = 343). CR was higher in Group A (16.1%) than in Group B (11.8%), p < 0.001. The difference was highly significant in women (N = 282, p < 0.001) and approached statistical significance in men (N = 61, p = 0.058). In the stepwise multiple regression analysis, VAI was independently associated with CR and was included in the equation before uric acid, non-HDL cholesterol, and eGFR in this order (r 2 = 0.163).Conclusions: VAI may be a useful parameter in the assessment of cardiovascular risk in elderly outpatients.Objective: Many forms of Smokeless Tobacco products exist worldwide. In Venezuela, Chimó is the most common form of Smokeless Tobacco. It is compound by tobacco leaf, sodium bicarbonate, brown sugar, ashes from the Mamón tree, vanilla and anisette flavoring. The ingredients vary according to the region within Venezuela. A small amount of Chimó is placed between the lip or cheek and the gum and left there for some time, usually 30 minutes. The mixture of Chimó and saliva is spit out. There are relation smokeless tobacco and hypertension in many studies The relation between hypertension and chimó has not been studied. The hypothesis was that chimó may increase hypertension risk. Design and method:An observational cross-sectional study. During the years [2013][2014] 1938 subjects aged 20 or older were evaluated in Timotes, a medical center from Andean region of Venezuela. Standard questioner and anthropometric measurements were obtained from each participant. Blood pressure was measured with OMRO HEM-907XL model equipment, twice, in the non-dominant arm supported to the heart level, in sitting position, after five minutes of rest. Results:Overall, 1938 subjects with a mean age of 47.8 ± 0.62 years in men and 50.1 ± 0.50 years in women (p = 0.004), 59.5% was females. Chimó frequency use was 55.0% in men and 45.0% in women (p < 0.0001). The result of regression logis-

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