Power Doppler Ultrasonography Assessment of Entheses in Spondyloarthropathies: Response to Therapy of Entheseal Abnormalities

Naredo, Esperanza; Batlle-Gualda, Enrique; García-Vivar, María Luz; García‐Aparicio, Ángel; Fernández-Sueiro, José Luís; Fernández-Prada, M; Giner, Emilio; Rodríguez–Gómez, Manuel; Pina, Maria Francisca; Medina-Luezas, Julio; Toyos, Francisco Javier; Campos, C.; Gutierrez-Polo, Ricardo; Ferrer, Miguel; Martínez, Olga; Díaz-Torné, Cèsar; González, Teresa; Campos, Serafín; Queiró, Rubén; Castaño-Sánchez, Manuel; Aznar, J.J.; Bustabad, Sagrario; Paez-Camino, Manuel; Tuneu, Roser; Ruíz, Teresa; Mateo, Lourdes; Pujol, Manuel; Ponce, Andrés; Ros, Inmaculada; Gallegos, Ángel; Moreno, J. Santiago; Gumbau, Domingo; Sianes, Manuela; Poveda-Elices, M. Jose; Romero‐Gómez, Manuel; Raya, Enrique

doi:10.3899/jrheum.100136

Cited by 130 publications

(74 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, 49 (36%) patients showed both synovitis and enthesopathy. As in our study, Naredo, et al 19 observed with US no significant differences between psoriatic patients with and those without joint synovitis in terms of demographic data and PASI scores.…”

Section: Discussionsupporting

confidence: 63%

“…These findings could relate to a subclinical entheseal psoriatic inflammation 18 . Naredo, et al 19 reported in 162 patients with plaque psoriasis without musculoskeletal disease that patients with psoriasis had a significant prevalence of asymptomatic US synovitis and enthesopathy, which may indicate a subclinical musculoskeletal involvement. Additionally, 49 (36%) patients showed both synovitis and enthesopathy.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Knee Enthesitis and Synovitis on Magnetic Resonance Imaging in Patients with Psoriasis without Arthritic Symptoms

et al. 2012

View full text Add to dashboard Cite

ABSTRACT. Objective. This case-control study was designed to evaluate magnetic resonance imaging (MRI) findings of knee joints in patients with psoriasis without clinical peripheral or axial joint involvement, and to correlate MRI findings with disease and demographic variables. Methods. In total 48 patients with psoriasis and no clinical evidence of synovitis or enthesitis in any peripheral or axial joints were enrolled. A random sample of 20 healthy subjects without knee or other joint complaints and matched for age and sex served as controls. All patients and controls underwent enhanced MRI studies of both knee joints, and MRI findings were compared. Results. Among 48 patients (96 knees), a total of 90 entheseal lesions were detected, with no enthesitis in 2 cases (6.3%). Signs of continuing inflammation bilaterally were frequently found: soft tissue edema (STE; n = 52), bone marrow edema (BME; n = 20), perientheseal BME (n = 3), cartilaginous erosions (n = 42), and bone erosions (n = 27). In controls, 2 (10%) subjects had BME and another 5 (25%) showed cartilaginous erosions. None showed evidence of enthesitis. Significant correlations were observed between the number of entheseal lesions of both knees vs STE (present vs absent; r = 0.314, p = 0.030) and STE (number of lesions; r = 0.351, p = 0.014). Enthesitis (unilateral vs bilateral) was significantly and positively correlated with STE (r = 0.304, p = 0.036), cartilaginous erosions (r = 0.304, p = 0.036), and villous projections (r = 0.347, p = 0.016). Conclusion. Subclinical synovitis and enthesitis are frequently found in the knee joint of patients with psoriasis. These may be an early sign of psoriatic

show abstract

Section: Discussionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Knee Enthesitis and Synovitis on Magnetic Resonance Imaging in Patients with Psoriasis without Arthritic Symptoms

et al. 2012

View full text Add to dashboard Cite

show abstract

“…An abundant number of studies have emerged in the literature over the past 2 decades for adult rheumatology, which included validation of the US detection of synovitis with histology and magnetic resonance imaging (MRI), standardization of the scanning technique, normative data acquisition, as well as documenting the responsiveness to change (11)(12)(13)(14)(15). These aspects have nevertheless only been partially addressed for pediatric patients (2,10,16); very few publications have started to collect information (16,17).…”

Section: Introductionmentioning

confidence: 99%

Definitions for the Sonographic Features of Joints in Healthy Children

Roth

Jousse‐Joulin

Magni‐Manzoni

et al. 2014

Arthritis Care & Research

Self Cite

View full text Add to dashboard Cite

Objective. Musculoskeletal ultrasonography (US) has potential in the assessment of disease activity and structural damage in childhood arthritides. In order to assess pathology, the US characteristics of joints in healthy children need to be defined first. The aim of this study was to develop definitions for the various components of the normal pediatric joint. Methods. The definitions were developed by an expert group and applicability was assessed on a collection of standardized scans of the knee and ankle joints by scoring the scans on a Likert scale. The definitions were then modified and applicability was reassessed before sending the definitions for approval to a larger panel of experts. A final scoring on stored images of all relevant joints at different ages followed. Results. Five definitions were developed addressing the articular bone, cartilage, joint capsule, epiphyseal ossification center, and synovial membrane. In total, 224 US images of knees and ankles were acquired, of which 172 were selected for scoring. An agreement of >80% was not met for any of the definitions, but after modifications, 81-97% agreement was reached. This version of the definitions was approved by 15 US experts. In the final validation exercise, all definitions reached an agreement of >80% for the shoulder, elbow, wrist, metacarpophalangeal hip, knee, ankle and metatarsophalangeal joint. Conclusion. US definitions for the normal pediatric joint were successfully developed through a Delphi process and validated in a practical exercise. These results provide the basis to develop definitions for pathology and to support the standardized use of US in pediatric rheumatology.

show abstract

“…In this issue of The Journal, Naredo and coworkers, in a large study involving 35 centers using the same US equipment, have demonstrated that US including PD assessment can be used as a valuable tool to assess response to therapy in SpA 18 . It is noteworthy that Spain has a uniform training program supported by the Spanish Society of Rheumatology and the highest percentage of rheumatologists trained in musculoskeletal US.…”

Section: The Sound Of Enthesismentioning

confidence: 99%

The Sound of Enthesis

Grassi¹,

Gutiérrez²,

Filippucci³

2010

J Rheumatol

View full text Add to dashboard Cite

Power Doppler Ultrasonography Assessment of Entheses in Spondyloarthropathies: Response to Therapy of Entheseal Abnormalities

Abstract: Entheseal morphologic abnormalities, PD signal, and bursitis were US abnormalities that were responsive to anti-TNF therapy in SpA. PDUS can be a reproducible method for multicenter monitoring of therapeutic response in enthesitis of SpA.

Cited by 130 publications

References 25 publications

Knee Enthesitis and Synovitis on Magnetic Resonance Imaging in Patients with Psoriasis without Arthritic Symptoms

Knee Enthesitis and Synovitis on Magnetic Resonance Imaging in Patients with Psoriasis without Arthritic Symptoms

Definitions for the Sonographic Features of Joints in Healthy Children

The Sound of Enthesis

Contact Info

Product

Resources

About