Potentiometric Determination of Pharmaceutically Important Nimesulide in Non-Aqueous Medium

Abstract

A series of Mannich bases containing bis-1,2,4-triazole were prepared under conventional cyclic condensation. The structures of newly synthesized compounds were established based on analytical and spectral studies. Further these compounds were evaluated for their antioxidant, antifungal and antibacterial activities. Most of the compounds showed good activity when compared with standard.