Potentially inappropriate psychotropic prescription at discharge is associated with lower functioning in the elderly psychiatric inpatients. A cross-sectional study

Abstract

In the current increasingly fragmented health care systems, special attention must be given to PIP prescription in older population suffering from psychiatric disorders. Using the Beers criteria, the present study demonstrates the high prevalence of PIP prescription, which concerns a large panel of drugs but mostly anxiolytics and hypnotics independently of psychiatric or somatic diagnoses and sociodemographic characteristics. Our study has demonstrated for the first time an association between PIP prescription and lowered patient functioning. Further longitudinal studies should confirm a potential causal relation.

The Prevalence of Potentially Inappropriate Prescribing in Geriatric Patients with Psychiatric Disorders in Iraq

“…There are several factor that lead to the high prevalence of PIPs in 74.3% of this study patients such as: most patients admitted due to acute psychological conditions or agitation which in turn required aggressive therapeutic plans to improve patient's condition, combined with the lack of safer alternative interventions which lead to the increased use of anxiolytics, hypnotics and antipsychotic injections; other factors that may have caused a false increase in PIPs is due to a flaw in the criteria itself for not providing a rule regarding a duration of medication use to be considered inappropriate which lead to many medications used only once by the patients to be counted as potentially inappropriate (13)(14)(15)(16) . However, the result of the present study is similar to (M Gutiérrez-Valencia et al, 2017) (14) which measured a PIP prevalence of 71.5% in hospitalized geriatric patients in acute setting in Spain, and also similar to (G. Fond et al,2016) (17) which measured prevalence of PIP of psychotropic medications in hospital setting after discharge in France and found it to be 76.1%, another study measuring PIPs in psychiatric hospital in the Netherlands (S. Rongen et al,2016) (16) found a much lower prevalence of 47%.…”

“…Gender and age were considered to be a significant factor in the prescribing of PIM is some studies (G. fond et al,2016) (17) and (H. Cho et al,.2018) (15) , and considered to be insignificant in others (X. Vidal et al,2016) (18) , this can be explained by differences in study settings, prescribed medications, and discrepancies in other factors.…”

The impact of a combined intervention program: an educational and clinical pharmacist’s intervention to improve prescribing pattern in hospitalized geriatric patients at King Abdulaziz Medical City in Riyadh, Saudi Arabia

“… 23 Potentially inappropriate psychotropic prescription in geriatric patients has become an important concern in developed countries antipsychotics (11.0%). 24 The second group of the Beers criteria is the medications to be avoided with specific diseases or syndromes. We found that the most common practice of prescribing PIMs for hospitalized geriatric patients diagnosed with heart failure involved NSAIDs and COX-2 inhibitors.…”

Trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs in the health region of Lleida from 2002 to 2015

“…According to previous studies, only 20-30% of prescription of BZDs prescriptions are appropriate [18,19]; in Canada, this means an extra cost of CAN $3076 per person per year in hospitalization, emergency department and outpatient costs [20]. In older people, two aspects as hospitalization and nursing home admission, are triggers for the initiation of BZDs; between 13 and 69% of hospitalized older people use BZDs [21,22], and the prevalence of BZD use in nursing home residents is 25-50% [23][24][25].…”