Potentially inappropriate medications for older adults in a primary healthcare unit in southern Brazil

Garcia, Taiane Santos; Rocha, Bruno Simas da; Castro, Stela Maris de Jezus; Heineck, Isabela

doi:10.1007/s11096-020-01048-7

Cited by 14 publications

(11 citation statements)

References 37 publications

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“…Cross-sectional studies in Japan have reported that patients who were prescribed by two or more physicians or who consulted more medical institutions are more likely to have PP and PIM use [8,70], as shown in our study. Furthermore, our study demonstrated that there is also a significant association between PP and PIM use, which is supported by previous reports [8,[20][21][22][23][24][25][26][27]. The frequency of elderly PIM(+) patients in Japan varies from 22.9% to 67.3% [8,22,23,27,31,35,68,71,72] because of different study populations and settings, different definitions of PIMs, or different timings of the investigation.…”

Section: Discussionsupporting

confidence: 88%

“…Potentially inappropriate medications (PIMs), defined as medications with more harmful than beneficial effects on elderly patients [19], are closely related to PP [8,[20][21][22][23][24][25][26][27] and are a relevant public health concern for elderly patients [28,29]. In 2015, the Japan Geriatric Society (JGS) updated the "Guidelines for Medical Treatment and its Safety in the Elderly" and proposed medication lists regarding PIMs, "Screening Tool for Older Persons' Appropriate Prescriptions for Japanese" (STOPP-J), to contribute to improving prescription quality [30,31].…”

Section: Introductionmentioning

confidence: 99%

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Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

Miyazaki

Uchiyama

Nakamura

et al. 2020

IJERPH

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Background: Polypharmacy (PP) and potentially inappropriate medications (PIMs) cause problematic drug-related issues in elderly patients; however, little is known about the association between medication adherence and PP and PIMs. This study evaluated the association of self-reported medication adherence with PP and PIMs in elderly patients. Methods: A cross-sectional pilot study was conducted using data collected from electronic medical records of 142 self-administering patients aged ≥65 years, excluding emergency hospitalization cases. Self-reported medication adherence was assessed using the visual analogue scale (VAS). Results: Of the 142 patients, 91 (64.1%) had PP and 80 (56.3%) used at least one PIM. In univariate analysis, patients with a VAS score of 100% had a significantly higher number of female patients and ≥1 PIM use compared to other patients. We found no association between the VAS score and PP. In multivariable analysis, the use of PIMs was significantly associated with a VAS score of 100% (odds ratio = 2.32; 95% confidence interval = 1.16–4.72; p = 0.017). Conclusions: Use of PIMs by elderly patients is significantly associated with self-reported medication adherence. Pharmacists should pay more attention to prescribed medications of self-administering elderly patients in order to improve their prescribing quality.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

Miyazaki

Uchiyama

Nakamura

et al. 2020

IJERPH

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“… 19,31 The opposite findings could be a reflection of the divergent methods used and the differences in the populations studied. The positive association of age and PIM use was mainly reported from studies using medical records 19,31 . We used administrative data and limited the prescriptions to those from the outpatient visit provider within 7 days.…”

Section: Discussionmentioning

confidence: 98%

Potentially inappropriate medication prescribing by nurse practitioners and physicians

Chou

Kuo

Raji

et al. 2021

J American Geriatrics Society

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Background Potentially inappropriate medication (PIM) use is a risk factor for hospitalization and mortality. However, there were few studies focusing on the impact of provider type on PIM use. Objective We aimed to estimate the initial and refill PIM prescribing rate for physician visits and nurse practitioner (NP) visits and the impact of provider type on PIM prescribing. Research Design We used 100% Texas Medicare data to define physician visits and NP visits in 2016. The rate of visits with a PIM prescription from the same provider was measured, distinguishing between initial and refill prescription to estimate the PIM rate and adjusted odds ratio (OR) by provider type. Results There were 24.1 per 1000 visits with a prescription for a PIM: 9.0 per 1000 visits for an initial PIM and 15.1 per 1000 visits for a refill PIM. A visit to an NP was less likely to result in an initial (OR = 0.74, 95% confidence interval [CI] = 0.70–0.79) or refill (OR = 0.54, 95% CI = 0.51–0.57) PIM. The association of lower odds of receiving a prescription for an initial PIM from an NP was substantially stronger among black enrollees than white enrollees (OR = 0.44, 95%CI = 0.30–0.65 for blacks and OR = 0.73, 95%CI = 0.68–0.78 for white enrollees). The association of an NP provider with lower odds of receiving a PIM refill was more pronounced in older patients and in those with more comorbidities. Conclusions NPs prescribed fewer initial PIMs and were less likely to refill a PIM after an outpatient visit than physicians. The lower odds of receiving PIMs during an NP visit varied by age, race/ethnicity, rurality, and number of comorbidities.

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“… 30 Similar results were observed in a study performed in a primary health care unit in southern Brazil, in which benzodiazepines stood out among other PIM. 31 Additionally, another study showed that for active drivers aged 65 to 79 years, PIM prevalence was 18.5%, and the most frequently used PIM drug class was benzodiazepines, accounting for 16.6% of the total PIMs identified. 32…”

Section: Discussionmentioning

confidence: 99%

Potentially Inappropriate Medication Prescribing in Older Adults According to EU(7)-Potentially Inappropriate Medication List: A Nationwide Study in Portugal

Rodrigues

Plácido²,

Tavares³

et al. 2022

Current Therapeutic Research

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Potentially inappropriate medications for older adults in a primary healthcare unit in southern Brazil

Cited by 14 publications

References 37 publications

Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

Potentially inappropriate medication prescribing by nurse practitioners and physicians

Potentially Inappropriate Medication Prescribing in Older Adults According to EU(7)-Potentially Inappropriate Medication List: A Nationwide Study in Portugal

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