Abstract:Patients with cirrhosis will gradually develop portal hypertension (PHT) and esophagogastric varices, and subsequently the more severe and often lethal complications such as bleeding esophageal varices, ascites, spontaneous bacterial peritonitis, renal dysfunction and hepatic encephalopathy. To date, there is still not any effective therapy for the prevention of the development these serious complications. The initial factor leading to PHT is an increase in hepatic resistance. Then, the increase in portal bloo… Show more
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