Potential Vaccine Candidates against Nematodes of  Veterinary Importance: An Overview

Singh, Ekta; Chandra, Dinesh; Prasad, A.; Kaur, Navneet

doi:10.20546/ijcmas.2019.804.023

Cited by 2 publications

(3 citation statements)

References 25 publications

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“…Vaccination has been proposed as a promising alternative control method for STHs. Although no vaccines are currently available for human STHs, vaccines, such as Barbervax (Nisbet et al 2016 ), were developed for H. contortus , a voracious blood-sucking nematode of small ruminants causing high morbidity and hitting hard the economy of sheep farming worldwide (Singh et al 2019 ). Overall, these alternative control methods help promote the principles of the One-Health approach by minimizing incidences of parasite infections in humans and animals, while reducing parasite stages in the environment, thus improving and protecting the health and well-being of the entire communities.…”

Section: One-health Approach To Anthelmintic Drug Resistancementioning

confidence: 99%

Anthelmintic resistance in soil-transmitted helminths: One-Health considerations

Ng’etich,

Amoah,

Bux

et al. 2023

Parasitol Res

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The One-Health approach recognizes the intricate connection between human, animal, and environmental health, and that cooperative effort from various professionals provides comprehensive awareness and potential solutions for issues relating to the health of people, animals, and the environment. This approach has increasingly gained appeal as the standard strategy for tackling emerging infectious diseases, most of which are zoonoses. Treatment with anthelmintics (AHs) without a doubt minimizes the severe consequences of soil-transmitted helminths (STHs); however, evidence of anthelmintic resistance (AR) development to different helminths of practically every animal species and the distinct groups of AHs is overwhelming globally. In this regard, the correlation between the application of anthelmintic drugs in both human and animal populations and the consequent development of anthelmintic resistance in STHs within the context of a One-Health framework is explored. This review provides an overview of the major human and animal STHs, treatment of the STHs, AR development and drug-related factors contributing towards AR, One-Health and STHs, and an outline of some One-Health strategies that may be used in combating AR.

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Section: One-health Approach To Anthelmintic Drug Resistancementioning

confidence: 99%

Anthelmintic resistance in soil-transmitted helminths: One-Health considerations

Ng’etich,

Amoah,

Bux

et al. 2023

Parasitol Res

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“…Many efforts to develop anthelminthic vaccines in livestock started many years back with limited success [159]. As discussed in detail above, elusive behavior of worms does not provide adequate long-lasting protection at all stages of helminthic maturation [160]. Vaccines provide manifold benefits on improving animal health, welfare and control of animal infection.…”

Section: Helminth Vaccines In Focusmentioning

confidence: 99%

“…This protection could reach up to 98% in vitro with two experimental doses. Attenuated larval Dictyocaulus filaria (sheep lungworm) name "DIFIL" for Dictyocaulus filaria larva is effectively used in India since 1981 [160]. A similar approaches are used to develop other vaccines.…”

Section: Attenuated Vaccinesmentioning

confidence: 99%

Goat Immunity to Helminthes

Ayaz¹,

Sheikh²,

Aziz³

et al. 2020

Goats (Capra) - From Ancient to Modern

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Goat hematology, especially, shares considerable attention since the last 1980s. Large number of discrepant normal hematologic values is reported. The discrepancies resulted came from the differences in age group, breed, and health standing of goats. This makes it further complex with variances in climate of the region, its environment, and size and methodology applied. With time, many inconsistencies, reasonably standardization in normal caprine kinetic hematologic values, are in place. Both goats and sheep are infested by the same key digestive tract helminthes (DTHs) diseases. Helminthes are exceedingly ubiquitous worm parasites that progressed to adopt with many erudite means to evade host immune system.

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Potential Vaccine Candidates against Nematodes of Veterinary Importance: An Overview

Cited by 2 publications

References 25 publications

Anthelmintic resistance in soil-transmitted helminths: One-Health considerations

Anthelmintic resistance in soil-transmitted helminths: One-Health considerations

Goat Immunity to Helminthes

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