Anabaena variabilis and Tolypthrix ceytonica were selected for bioremediation of heavy metals-contaminated industrial effluents based on their high efficiency as metals accumulators. Sodium alginate immobilized individual or mixed cell cultures were examined to decontaminate Plastic and electrical industrial effluents in continuous mode (at 50 and 100 ml/h flow rates) for 6 h. Removal efficiency was a function of heavy metal type, concentration, microbial species and proportionally increased with exposure time. The maximum achieved removals recorded 94.45% for Fe 2+ (A. variabilis at 50 ml/h), Zn 2+ (98.98% by A. variabilis; 98.63% by A. variabilis and T. ceytonica mixture and 98.61% by T. ceytonica at 100 ml/h), 94.22% for Pb 2+ (A. variabilis and T. ceytonica mixture at 100 ml/h) as well as 93.33% and 91.33% for Cu 2+ by A. variabilis and T. ceytonica at 50 and 100 ml/h flow rates, respectively. Excellent selective metals bioremoval abilities were detected by the selected cyanobacterial species. Their manipulation in the proposed biotechnology provides an economic and excellent tool for remediation of industrial effluents and protection of the received environments. Moreover, treated wastewater may be reused in any purpose such as aqua-culturing or irrigation of agricultural edible and non-edible crops.