Potential underdiagnosis of obstructive sleep apnoea in the cardiology outpatient setting

Costa, Lucas E; Uchôa, Carlos Henrique Gomes; Harmon, Rebeca R.; Bortolotto, Luiz Aparecido; Lorenzi-Filho, Geraldo; Drager, Luciano F.

doi:10.1136/heartjnl-2014-307276

Cited by 107 publications

(68 citation statements)

References 23 publications

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“…It is investigated by sleep specialists, respiratory physicians and otorhinolaryngologists. Cardiologists disregard OSA in their clinical reasoning, as Costa et al 7 show in their Heart paper. Studying a representative sample of various cardiological subspecialties in a tertiary care university-affiliated hospital in São Paulo, Brazil, they identified that among 500 consecutive patients evaluated, 258 patients (51.6%) had a high risk for OSA by the Berlin questionnaire.…”

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confidence: 99%

Obstructive sleep apnoea should be deemed a cardiovascular disease

Fuchs

Martinez

2015

Heart

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confidence: 99%

Obstructive sleep apnoea should be deemed a cardiovascular disease

Fuchs

Martinez

2015

Heart

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“…Although they studied a larger number of patients, prevalence rates of both OSA and cancer were obtained retrospectively from a health database. Therefore, the presence of OSA could be underestimated, since it is a frequently underdiagnosed condition [19].…”

Section: Discussionmentioning

confidence: 99%

Sleep Disordered Breathing Is Highly Prevalent in Patients with Lung Cancer: Results of the Sleep Apnea in Lung Cancer Study

et al. 2018

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Background: Obstructive sleep apnea (OSA) has been linked to tumorigenesis and tumor progression. Objectives: The Sleep Apnea in Lung Cancer (SAIL) study (NCT02764866) was designed to determine the prevalence of OSA in patients with lung cancer. Methods: Cross-sectional study including consecutive patients with newly diagnosed lung cancer. All patients were offered home sleep apnea testing (HSAT) and administered a sleep-specific questionnaire prior to initiating oncologic treatment. Sleep study-related variables, symptoms, and epidemiologic data as well as cancer related variables were recorded. Results: Eighty-three patients were enrolled in the SAIL study. Sixty-six completed HSAT. The mean age was 68 ± 11 years and 58% were male with a mean body mass index of 28.1 ± 5.4. Forty-seven percent were current smokers, 42% former smokers, and 11% never smokers with a median tobacco consumption of 51 pack-years. Fifty percent had COPD with a mean FEV1 of 83 ± 22.6% of predicted and a mean DLCO of 85.5 ± 20.1%. Adenocarcinoma was the most common histologic type (46.7%), followed by squamous cell (16.7%) and small cell (16.7%). Most patients were diagnosed at an advanced stage (65% in stages III–IV). The vast majority (80%) had OSA (apnea-hypopnea index [AHI] > 5), and 50% had moderate to severe OSA (AHI > 15) with a mean Epworth Sleepiness Score of 7.43 ± 3.85. Significant nocturnal hypoxemia was common (Median T90: 10.9% interquartile range 2.4–42.2). Conclusions: Sleep apnea and nocturnal hypoxemia are highly prevalent in patients with lung cancer.

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“…1 However, OSA remains largely underrecognized in this group of patients in clinical practice. 1 Why is that?…”

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confidence: 99%

“…1 However, OSA remains largely underrecognized in this group of patients in clinical practice. 1 Why is that? One possible explanation is that many nonsleep specialists are not familiarized with OSA diagnosis and treatment.…”

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confidence: 99%