Potential therapeutic activity of  Phlogacanthus thyrsiformis  Hardow (Mabb) flower extract and its biofabricated silver nanoparticles against chemically induced urolithiasis in male Wistar rats

Das, Purnima; Kumar, K. Vinod; Nambiraj, Arunai; Rajan, R. Sundara; Awasthi, Rajendra; Dua, Kamal; Himaja, M.

doi:10.1016/j.ijbiomac.2017.05.096

Cited by 35 publications

(19 citation statements)

References 21 publications

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“…Recently, bioactive substances extracted from plants, such as polyphenols and flavonoids, have anti-urolithiatic effects by increasing urine volume [18][19][20]. Watermelon contains useful components such as L-citrulline, which has a diuretic effect.…”

Section: Discussionmentioning

confidence: 99%

Effects of a Watermelon Extract Beverage on Canine Lipid Metabolism and Urine Crystals

Miyai¹

2018

AVS

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Previous report showed that watermelon consumption has an anti-obesity effects in rats. The purpose of this study is to examine the effects on body weight, body fat percentage, serum biochemical data, serum adipokine concentrations (leptin, adiponectin, and resistin), urine specific gravity and sediments when 12 dogs were given watermelon extract beverage instead of water for 3 months. Those data were all assessed before the study period and again at 1.5 and 3 months. Although there were no remarkable changes in most of these parameters, a significant decrease in serum leptin concentrations at 1.5 and 3 months. Calcium oxalate and struvite crystals were observed in the urinary sediment in five dogs; although their urine specific gravities remained >1.040 throughout, the number of urinary crystals had decreased by the end of the 3-month period. Morphological components were not found in the urinary sediment of the other five dogs; their urine specific gravities were also >1.040 before the study period and at 1.5 months, but these had decreased to <1.040 at 3 months. These results suggested that drinking the watermelon extract beverage reduced serum leptin levels and inhibited the formation of urine crystals such as calcium oxalate and struvite crystals in dogs.

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Section: Discussionmentioning

confidence: 99%

Effects of a Watermelon Extract Beverage on Canine Lipid Metabolism and Urine Crystals

Miyai¹

2018

AVS

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“…Green nanotechnology is gaining worldwide importance because of exclusion of harmful chemicals, economical Diagnosis and targeting of cancer cells using emerging nanoparticle and use of different eukaryotic and prokaryotic organisms. Among these, the plant extracts act as reducing and capping agents for the NP synthesis, and the resultant prefabricated NPs exhibit better bioactivity [139,140].…”

Section: Natural Bioactives Delivered Through Nanocarriermentioning

confidence: 99%

Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

Maurya

Singh

Mishra

et al. 2019

Interventional Medicine and Applied Science

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Since the development of first lipid-based nanocarrier system, about 15% of the present pharmaceutical market uses nanomedicines to achieve medical benefits. Nanotechnology is an advanced area to meliorate the delivery of compounds for improved medical diagnosis and curing disease. Nanomedicines are gaining significant interest due to the ultra small size and large surface area to mass ratio. In this review, we discuss the potential of nanotechnology in delivering of active moieties for the disease therapy including their toxicity evidences. This communication will help the formulation scientists in understanding and exploring the new aspects of nanotechnology in the field of nanomedicine.

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“…Dilution of the sample was filled in a cuvette made up of polystyrene in hydro dispensing unit and then scan was carried out at a rate of 64 runs per sample. As the scan is completed, the average diameter per scan was taken out and recorded as Z-average for all the 64 runs [21][22][23][24].…”

Section: Particle Size Polydispersity Index (Pdi) and Zeta Potentialmentioning

confidence: 99%

Central composite designed formulation, characterization and in vitro cytotoxic effect of erlotinib loaded chitosan nanoparticulate system

Pandey

Chellappan

Tambuwala

et al. 2019

International Journal of Biological Macromolecules

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Potential therapeutic activity of Phlogacanthus thyrsiformis Hardow (Mabb) flower extract and its biofabricated silver nanoparticles against chemically induced urolithiasis in male Wistar rats

Cited by 35 publications

References 21 publications

Effects of a Watermelon Extract Beverage on Canine Lipid Metabolism and Urine Crystals

Effects of a Watermelon Extract Beverage on Canine Lipid Metabolism and Urine Crystals

Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

Central composite designed formulation, characterization and in vitro cytotoxic effect of erlotinib loaded chitosan nanoparticulate system

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