Potential role for organochlorine pesticides in the prevalence of peripheral arterial diseases in obese persons: Results from the National Health and Nutrition Examination Survey 1999–2004

The effect of pesticide exposure on cardiovascular system: a systematic review

“…24,32 Other than that, OCs were also found to have association with cerebrovascular disease. A prospective study by Lee et al, 2012 found that individuals with elevated levels of pesticide which were polychlorinated biphenyl (PCBs) and DDT in their blood run a greater risk of having a stroke.…”

“…The American studies used an algorithm to estimate long-term chemical-specific pesticide exposures while ten studies that examined the outcome of ECG findings used history of exposure to OPs within 24 hours, clinical effects, and serum cholinesterase activity. 20,22,24,25 An ecological paper assigned exposure according to the wheat acreage per county or percentage of the county's land area dedicated to wheat farming as a surrogate measure of exposure to chlorophenoxy herbicides, because information on herbicide use by county was not available. 27 Use of this surrogate exposure measure was a reasonable choice because chlorophenoxy herbicides are the predominant herbicides applied to wheat.…”

“…Four studies concerned pesticide applicators only, whereas two studies dealt with civilians and two studies dealt with mix pesticide applicators with their householdmembers. [20][21][22][23][24][25][26][27] Potentially relevant publications screened for retrieval, N = 891…”

Computational investigation on NO3-initiated degradation of p,p′-DDE in atmosphere: Mechanism and kinetics

“…Thus, pervasive DDE residues have become a threat to food security and human health [4], which elevated public concern. Recently, human exposure to DDE has been shown to result in adverse health outcome [9], e.g., type 2 diabetes [10,11] and peripheral arterial diseases of obese population [12]. DDE residue has even been detected in atmosphere worldwide [13,14].…”

Lifestyle and Dietary Risk Factors for Peripheral Artery Disease

“…56 A similar association has been reported for organochlorine pesticides. 57 Atherosclerotic PAD is also associated with genetic variants and it is known to have a heritable component. 58 Factors associated with PAD include variation in the genetic code and epigenetic DNA modifications and these factors could enhance the capacity to detect susceptible subjects at risk for PAD.…”